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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASC1 All Species: 4.55
Human Site: S362 Identified Species: 14.29
UniProt: Q6TDU7 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6TDU7 NP_001076441.1 716 83218 S362 Q L L L V E N S S E K P D F F
Chimpanzee Pan troglodytes XP_520802 883 101408 S529 Q L L L V E N S S E K P D F F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543757 718 82671 A364 Q L L L I E N A T E K P T F F
Cat Felis silvestris
Mouse Mus musculus Q6TDU8 730 84948 V377 Q L C L V E N V V E L P E A S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514489 364 41646 P43 L D V L R L P P Q R K Q V K G
Chicken Gallus gallus XP_416435 660 76295 F327 S T V D L Q Q F V P V G G V Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A6H8T2 731 84203 E359 E E I T T T L E A D Q H D P Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001176259 678 77267 Q333 D L L T M P P Q P K H I K N W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.1 N.A. 51.6 N.A. 67.1 N.A. N.A. 26.8 44.4 N.A. 39.9 N.A. N.A. N.A. N.A. 32.4
Protein Similarity: 100 80.9 N.A. 64.9 N.A. 81.9 N.A. N.A. 37.2 64.2 N.A. 60 N.A. N.A. N.A. N.A. 51.5
P-Site Identity: 100 100 N.A. 73.3 N.A. 53.3 N.A. N.A. 13.3 0 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 60 N.A. N.A. 20 26.6 N.A. 46.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 13 13 0 0 0 0 13 0 % A
% Cys: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 13 0 13 0 0 0 0 0 13 0 0 38 0 0 % D
% Glu: 13 13 0 0 0 50 0 13 0 50 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 0 0 13 0 0 0 0 0 38 38 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 13 13 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 13 13 0 0 0 % H
% Ile: 0 0 13 0 13 0 0 0 0 0 0 13 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 13 50 0 13 13 0 % K
% Leu: 13 63 50 63 13 13 13 0 0 0 13 0 0 0 0 % L
% Met: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 50 0 0 0 0 0 0 13 0 % N
% Pro: 0 0 0 0 0 13 25 13 13 13 0 50 0 13 0 % P
% Gln: 50 0 0 0 0 13 13 13 13 0 13 13 0 0 0 % Q
% Arg: 0 0 0 0 13 0 0 0 0 13 0 0 0 0 0 % R
% Ser: 13 0 0 0 0 0 0 25 25 0 0 0 0 0 13 % S
% Thr: 0 13 0 25 13 13 0 0 13 0 0 0 13 0 0 % T
% Val: 0 0 25 0 38 0 0 13 25 0 13 0 13 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _