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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASC1
All Species:
20.91
Human Site:
S663
Identified Species:
65.71
UniProt:
Q6TDU7
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6TDU7
NP_001076441.1
716
83218
S663
K
E
E
S
E
A
F
S
E
A
L
K
E
E
T
Chimpanzee
Pan troglodytes
XP_520802
883
101408
S830
K
E
E
S
E
A
F
S
E
A
L
K
E
E
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543757
718
82671
S665
N
E
N
S
E
T
F
S
E
A
L
K
E
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6TDU8
730
84948
S677
Q
E
E
N
D
K
F
S
E
A
L
R
E
G
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514489
364
41646
E312
E
F
G
P
A
F
S
E
D
L
E
D
D
T
E
Chicken
Gallus gallus
XP_416435
660
76295
S607
T
E
A
S
E
A
F
S
M
E
L
E
E
D
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A6H8T2
731
84203
S678
K
E
Q
E
D
S
F
S
P
E
L
A
E
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176259
678
77267
S625
G
E
Y
D
E
E
F
S
E
A
F
A
E
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.1
N.A.
51.6
N.A.
67.1
N.A.
N.A.
26.8
44.4
N.A.
39.9
N.A.
N.A.
N.A.
N.A.
32.4
Protein Similarity:
100
80.9
N.A.
64.9
N.A.
81.9
N.A.
N.A.
37.2
64.2
N.A.
60
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
N.A.
80
N.A.
60
N.A.
N.A.
0
60
N.A.
40
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
N.A.
80
N.A.
86.6
N.A.
N.A.
20
73.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
13
38
0
0
0
63
0
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
25
0
0
0
13
0
0
13
13
13
0
% D
% Glu:
13
88
38
13
63
13
0
13
63
25
13
13
88
38
13
% E
% Phe:
0
13
0
0
0
13
88
0
0
0
13
0
0
0
0
% F
% Gly:
13
0
13
0
0
0
0
0
0
0
0
0
0
38
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
38
0
0
0
0
13
0
0
0
0
0
38
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
13
75
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% M
% Asn:
13
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
13
0
0
0
0
13
0
0
0
0
0
0
% P
% Gln:
13
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% R
% Ser:
0
0
0
50
0
13
13
88
0
0
0
0
0
0
25
% S
% Thr:
13
0
0
0
0
13
0
0
0
0
0
0
0
13
63
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _