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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASC1
All Species:
10.61
Human Site:
T428
Identified Species:
33.33
UniProt:
Q6TDU7
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6TDU7
NP_001076441.1
716
83218
T428
E
T
T
E
E
F
E
T
E
N
A
F
P
P
I
Chimpanzee
Pan troglodytes
XP_520802
883
101408
T595
E
T
T
E
E
F
E
T
E
N
A
F
P
P
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543757
718
82671
T430
E
T
T
E
D
V
E
T
E
N
A
F
P
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6TDU8
730
84948
P443
D
T
T
E
E
P
D
P
D
V
T
F
P
P
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514489
364
41646
N92
V
T
L
K
F
N
D
N
A
M
F
F
E
E
P
Chicken
Gallus gallus
XP_416435
660
76295
H376
Q
E
S
E
D
T
T
H
P
P
I
Q
I
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A6H8T2
731
84203
T446
K
L
D
E
H
S
N
T
T
V
A
S
L
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176259
678
77267
E389
A
A
N
A
A
A
T
E
A
L
G
A
P
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.1
N.A.
51.6
N.A.
67.1
N.A.
N.A.
26.8
44.4
N.A.
39.9
N.A.
N.A.
N.A.
N.A.
32.4
Protein Similarity:
100
80.9
N.A.
64.9
N.A.
81.9
N.A.
N.A.
37.2
64.2
N.A.
60
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
N.A.
86.6
N.A.
53.3
N.A.
N.A.
13.3
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
73.3
N.A.
N.A.
26.6
33.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
0
13
13
13
0
0
25
0
50
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
13
0
25
0
25
0
13
0
0
0
0
0
0
% D
% Glu:
38
13
0
75
38
0
38
13
38
0
0
0
13
13
0
% E
% Phe:
0
0
0
0
13
25
0
0
0
0
13
63
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% G
% His:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
13
0
13
0
50
% I
% Lys:
13
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
13
0
0
0
0
0
0
13
0
0
13
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
13
13
13
0
38
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
13
0
13
13
13
0
0
63
75
13
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
13
0
0
13
0
0
0
0
0
13
0
0
0
% S
% Thr:
0
63
50
0
0
13
25
50
13
0
13
0
0
13
0
% T
% Val:
13
0
0
0
0
13
0
0
0
25
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _