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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FIP1L1
All Species:
17.27
Human Site:
S276
Identified Species:
47.5
UniProt:
Q6UN15
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UN15
NP_001128409.1
594
66526
S276
P
P
S
R
N
S
T
S
S
Q
S
Q
T
S
T
Chimpanzee
Pan troglodytes
XP_001147016
603
67380
S276
P
P
S
R
N
S
T
S
S
Q
S
Q
T
S
T
Rhesus Macaque
Macaca mulatta
XP_001090808
594
66538
S276
P
P
S
R
N
S
T
S
S
Q
S
Q
T
S
T
Dog
Lupus familis
XP_853955
764
84414
S437
P
P
S
R
N
S
T
S
S
Q
S
Q
T
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D824
581
64940
K270
K
A
S
S
S
V
G
K
W
Q
D
R
Y
G
R
Rat
Rattus norvegicus
Q5U317
536
60169
K241
T
S
P
P
S
L
F
K
T
G
L
P
P
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517022
711
77022
D358
P
S
S
P
R
R
R
D
P
R
P
R
L
W
P
Chicken
Gallus gallus
XP_001233386
773
84522
S445
P
T
N
R
S
S
A
S
P
Q
S
K
T
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5XJD3
570
62947
P264
N
Q
G
R
I
S
P
P
H
W
A
G
P
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.8
73.5
N.A.
93.5
87.7
N.A.
26.5
62.7
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
99.8
75.9
N.A.
94.4
88.3
N.A.
37.1
68.5
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
13.3
6.6
N.A.
13.3
60
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
20
N.A.
26.6
80
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
12
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
12
0
0
12
0
12
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
23
0
0
0
12
0
0
0
% K
% Leu:
0
0
0
0
0
12
0
0
0
0
12
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
12
0
45
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
45
12
23
0
0
12
12
23
0
12
12
23
12
12
% P
% Gln:
0
12
0
0
0
0
0
0
0
67
0
45
0
0
0
% Q
% Arg:
0
0
0
67
12
12
12
0
0
12
0
23
0
0
23
% R
% Ser:
0
23
67
12
34
67
0
56
45
0
56
0
0
67
12
% S
% Thr:
12
12
0
0
0
0
45
0
12
0
0
0
56
0
56
% T
% Val:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
12
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _