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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRTC1 All Species: 9.7
Human Site: S256 Identified Species: 23.7
UniProt: Q6UUV9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UUV9 NP_001091952.1 634 67300 S256 L T N I H F P S P L P T P L D
Chimpanzee Pan troglodytes XP_510592 618 66846 G256 G N A F P H N G Q N L G L S P
Rhesus Macaque Macaca mulatta XP_001115541 981 104760 S603 L T N I H F P S P L P T P L D
Dog Lupus familis XP_855142 696 72986 P286 L T N L H F P P P L P T P L D
Cat Felis silvestris
Mouse Mus musculus Q68ED7 630 66927 S256 L T N I H F P S P L P T P L D
Rat Rattus norvegicus Q3LRZ1 691 73127 P285 L T N L H F P P P L P T P L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233252 620 66878 P256 D L T N I H F P S P L P T P L
Frog Xenopus laevis Q52KS4 632 69330 S261 G S L N T G G S L P D L T N L
Zebra Danio Brachydanio rerio NP_001070925 533 57747 G171 P Q D A F A G G S Q D L Q P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783622 558 61739 V193 M S N P G S P V V L N Q R R H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.7 62.7 37.3 N.A. 90.2 39 N.A. N.A. 83.4 44.4 59.1 N.A. N.A. N.A. N.A. 20.1
Protein Similarity: 100 42.2 64.1 49.2 N.A. 93.2 50.3 N.A. N.A. 88 60.2 68.7 N.A. N.A. N.A. N.A. 33.7
P-Site Identity: 100 0 100 86.6 N.A. 100 86.6 N.A. N.A. 0 6.6 0 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 0 100 93.3 N.A. 100 93.3 N.A. N.A. 0 13.3 6.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 0 0 0 0 20 0 0 0 50 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 10 50 10 0 0 0 0 0 0 0 0 % F
% Gly: 20 0 0 0 10 10 20 20 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 50 20 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 30 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 50 10 10 20 0 0 0 0 10 60 20 20 10 50 20 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 60 20 0 0 10 0 0 10 10 0 0 10 0 % N
% Pro: 10 0 0 10 10 0 60 30 50 20 50 10 50 20 10 % P
% Gln: 0 10 0 0 0 0 0 0 10 10 0 10 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % R
% Ser: 0 20 0 0 0 10 0 40 20 0 0 0 0 10 0 % S
% Thr: 0 50 10 0 10 0 0 0 0 0 0 50 20 0 0 % T
% Val: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _