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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRTC1
All Species:
9.7
Human Site:
S424
Identified Species:
23.7
UniProt:
Q6UUV9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UUV9
NP_001091952.1
634
67300
S424
V
P
S
S
L
P
Q
S
P
P
E
N
P
G
Q
Chimpanzee
Pan troglodytes
XP_510592
618
66846
S413
S
R
Q
L
S
S
T
S
P
L
A
P
Y
P
T
Rhesus Macaque
Macaca mulatta
XP_001115541
981
104760
S771
V
P
S
S
L
P
Q
S
P
P
E
N
P
G
Q
Dog
Lupus familis
XP_855142
696
72986
S481
P
L
D
T
S
K
L
S
T
D
Q
R
L
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q68ED7
630
66927
Q420
T
V
P
S
T
L
P
Q
S
P
T
E
N
P
G
Rat
Rattus norvegicus
Q3LRZ1
691
73127
K476
G
V
P
L
D
T
S
K
L
P
T
D
Q
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233252
620
66878
S413
I
P
Q
S
P
P
G
S
Q
S
Q
S
Q
P
S
Frog
Xenopus laevis
Q52KS4
632
69330
P421
L
P
P
L
E
P
P
P
P
Y
P
L
Y
T
D
Zebra Danio
Brachydanio rerio
NP_001070925
533
57747
Q328
Q
Q
L
P
G
L
Q
Q
L
S
P
T
L
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783622
558
61739
S350
S
S
P
T
S
P
V
S
N
P
N
N
S
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.7
62.7
37.3
N.A.
90.2
39
N.A.
N.A.
83.4
44.4
59.1
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
100
42.2
64.1
49.2
N.A.
93.2
50.3
N.A.
N.A.
88
60.2
68.7
N.A.
N.A.
N.A.
N.A.
33.7
P-Site Identity:
100
13.3
100
6.6
N.A.
13.3
6.6
N.A.
N.A.
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
13.3
100
20
N.A.
13.3
13.3
N.A.
N.A.
46.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
0
0
10
0
10
0
0
10
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
20
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
10
0
0
0
0
0
0
20
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% K
% Leu:
10
10
10
30
20
20
10
0
20
10
0
10
20
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
10
30
10
0
0
% N
% Pro:
10
40
40
10
10
50
20
10
40
50
20
10
20
50
20
% P
% Gln:
10
10
20
0
0
0
30
20
10
0
20
0
20
0
20
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
0
% R
% Ser:
20
10
20
40
30
10
10
60
10
20
0
10
10
10
10
% S
% Thr:
10
0
0
20
10
10
10
0
10
0
20
10
0
10
10
% T
% Val:
20
20
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _