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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRTC1
All Species:
6.36
Human Site:
S543
Identified Species:
15.56
UniProt:
Q6UUV9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UUV9
NP_001091952.1
634
67300
S543
G
L
T
G
S
H
G
S
L
P
D
S
Q
Q
L
Chimpanzee
Pan troglodytes
XP_510592
618
66846
H532
R
E
L
Q
D
S
F
H
L
R
P
S
P
Y
S
Rhesus Macaque
Macaca mulatta
XP_001115541
981
104760
S890
G
L
T
G
S
H
G
S
L
P
D
S
Q
Q
L
Dog
Lupus familis
XP_855142
696
72986
P600
P
V
S
S
L
Q
D
P
H
A
L
N
H
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q68ED7
630
66927
G539
G
L
S
G
S
H
G
G
L
Q
D
P
Q
Q
L
Rat
Rattus norvegicus
Q3LRZ1
691
73127
S595
S
V
S
G
P
Q
D
S
H
V
L
N
H
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233252
620
66878
D532
G
S
H
G
S
L
Q
D
S
P
Q
L
S
Y
S
Frog
Xenopus laevis
Q52KS4
632
69330
D540
G
S
H
G
S
L
Q
D
S
F
H
L
R
P
N
Zebra Danio
Brachydanio rerio
NP_001070925
533
57747
N447
F
S
E
G
S
T
L
N
Y
S
Q
A
A
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783622
558
61739
L469
P
P
T
Y
Q
Q
T
L
M
Q
I
P
Q
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.7
62.7
37.3
N.A.
90.2
39
N.A.
N.A.
83.4
44.4
59.1
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
100
42.2
64.1
49.2
N.A.
93.2
50.3
N.A.
N.A.
88
60.2
68.7
N.A.
N.A.
N.A.
N.A.
33.7
P-Site Identity:
100
13.3
100
6.6
N.A.
73.3
20
N.A.
N.A.
26.6
20
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
100
26.6
N.A.
80
40
N.A.
N.A.
26.6
26.6
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
20
20
0
0
30
0
0
0
0
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% F
% Gly:
50
0
0
70
0
0
30
10
0
0
0
0
0
0
0
% G
% His:
0
0
20
0
0
30
0
10
20
0
10
0
20
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
30
10
0
10
20
10
10
40
0
20
20
0
0
40
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
20
0
0
30
% N
% Pro:
20
10
0
0
10
0
0
10
0
30
10
20
10
10
0
% P
% Gln:
0
0
0
10
10
30
20
0
0
20
20
0
40
50
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
10
30
30
10
60
10
0
30
20
10
0
30
10
0
30
% S
% Thr:
0
0
30
0
0
10
10
0
0
0
0
0
0
0
0
% T
% Val:
0
20
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
10
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _