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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRTC1
All Species:
19.7
Human Site:
T250
Identified Species:
48.15
UniProt:
Q6UUV9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UUV9
NP_001091952.1
634
67300
T250
G
G
S
L
P
D
L
T
N
I
H
F
P
S
P
Chimpanzee
Pan troglodytes
XP_510592
618
66846
N250
S
C
D
V
G
G
G
N
A
F
P
H
N
G
Q
Rhesus Macaque
Macaca mulatta
XP_001115541
981
104760
T597
G
G
S
L
P
D
L
T
N
I
H
F
P
S
P
Dog
Lupus familis
XP_855142
696
72986
T280
G
G
S
L
P
D
L
T
N
L
H
F
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q68ED7
630
66927
T250
G
G
S
L
P
D
L
T
N
I
H
F
P
S
P
Rat
Rattus norvegicus
Q3LRZ1
691
73127
T279
G
G
S
L
P
D
L
T
N
L
H
F
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233252
620
66878
L250
T
G
G
S
L
P
D
L
T
N
I
H
F
P
S
Frog
Xenopus laevis
Q52KS4
632
69330
S255
S
L
S
H
Y
Q
G
S
L
N
T
G
G
S
L
Zebra Danio
Brachydanio rerio
NP_001070925
533
57747
Q165
S
T
L
N
P
N
P
Q
D
A
F
A
G
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783622
558
61739
S187
N
Q
R
R
Q
V
M
S
N
P
G
S
P
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.7
62.7
37.3
N.A.
90.2
39
N.A.
N.A.
83.4
44.4
59.1
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
100
42.2
64.1
49.2
N.A.
93.2
50.3
N.A.
N.A.
88
60.2
68.7
N.A.
N.A.
N.A.
N.A.
33.7
P-Site Identity:
100
0
100
86.6
N.A.
100
86.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
100
93.3
N.A.
100
93.3
N.A.
N.A.
6.6
20
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
50
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
10
50
10
0
0
% F
% Gly:
50
60
10
0
10
10
20
0
0
0
10
10
20
20
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
50
20
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
30
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
50
10
0
50
10
10
20
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
10
0
10
60
20
0
0
10
0
0
% N
% Pro:
0
0
0
0
60
10
10
0
0
10
10
0
60
30
50
% P
% Gln:
0
10
0
0
10
10
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
30
0
60
10
0
0
0
20
0
0
0
10
0
40
20
% S
% Thr:
10
10
0
0
0
0
0
50
10
0
10
0
0
0
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _