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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNT2 All Species: 23.64
Human Site: S628 Identified Species: 52
UniProt: Q6UVM3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UVM3 NP_940905.2 1135 130501 S628 S K E I R R P S I A P V L E V
Chimpanzee Pan troglodytes XP_514073 1111 127635 S628 S K E I R R P S I A P V L E V
Rhesus Macaque Macaca mulatta O18867 1151 128915 M603 F V K L K L L M I A I E Y K S
Dog Lupus familis XP_548379 1319 147753 S779 G S G S R R P S I A P V L E L
Cat Felis silvestris
Mouse Mus musculus Q6ZPR4 1224 138087 S676 G S G S R R P S I A P V L E L
Rat Rattus norvegicus Q6UVM4 1142 131082 S635 G K E L R R P S I A P V L E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517416 550 62297 E72 D L L S D Q S E D E M T Q S D
Chicken Gallus gallus Q8QFV0 1201 137224 S682 G S G N R R P S I A P V L E L
Frog Xenopus laevis Q90ZC7 1196 134483 T704 R H D P L L M T G N D Q I D N
Zebra Danio Brachydanio rerio XP_694050 1122 127734 S635 S G E E R R H S I A P V L E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95V25 1140 129511 F627 I Q P Q T Q G F F I A Q S A D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 21 67.4 N.A. 71.9 96.9 N.A. 36.3 76.7 20.1 76.4 N.A. N.A. N.A. 20.2 N.A.
Protein Similarity: 100 97.8 41 76.6 N.A. 81.4 98.2 N.A. 41.2 84.5 38.7 85.1 N.A. N.A. N.A. 40.5 N.A.
P-Site Identity: 100 100 13.3 66.6 N.A. 66.6 86.6 N.A. 0 66.6 0 80 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 40 73.3 N.A. 73.3 93.3 N.A. 6.6 73.3 26.6 80 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 73 10 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 10 0 0 0 10 0 10 0 0 10 19 % D
% Glu: 0 0 37 10 0 0 0 10 0 10 0 10 0 64 0 % E
% Phe: 10 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % F
% Gly: 37 10 28 0 0 0 10 0 10 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 19 0 0 0 0 73 10 10 0 10 0 0 % I
% Lys: 0 28 10 0 10 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 10 10 19 10 19 10 0 0 0 0 0 64 0 28 % L
% Met: 0 0 0 0 0 0 10 10 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 10 % N
% Pro: 0 0 10 10 0 0 55 0 0 0 64 0 0 0 0 % P
% Gln: 0 10 0 10 0 19 0 0 0 0 0 19 10 0 0 % Q
% Arg: 10 0 0 0 64 64 0 0 0 0 0 0 0 0 0 % R
% Ser: 28 28 0 28 0 0 10 64 0 0 0 0 10 10 10 % S
% Thr: 0 0 0 0 10 0 0 10 0 0 0 10 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 64 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _