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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNT2
All Species:
9.09
Human Site:
T498
Identified Species:
20
UniProt:
Q6UVM3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UVM3
NP_940905.2
1135
130501
T498
H
I
V
L
E
E
S
T
F
F
A
E
Y
E
G
Chimpanzee
Pan troglodytes
XP_514073
1111
127635
T498
H
I
V
L
E
E
S
T
F
F
A
E
Y
E
G
Rhesus Macaque
Macaca mulatta
O18867
1151
128915
I485
N
I
M
R
V
I
S
I
K
N
Y
H
P
K
I
Dog
Lupus familis
XP_548379
1319
147753
K640
H
V
R
M
G
D
S
K
F
F
R
E
Y
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPR4
1224
138087
K537
H
I
R
M
G
D
S
K
F
F
R
E
Y
E
G
Rat
Rattus norvegicus
Q6UVM4
1142
131082
T505
H
I
V
L
E
E
S
T
F
F
A
E
Y
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517416
550
62297
Chicken
Gallus gallus
Q8QFV0
1201
137224
K549
H
I
R
M
G
D
S
K
F
F
M
E
Y
E
G
Frog
Xenopus laevis
Q90ZC7
1196
134483
G580
Y
L
S
S
A
F
V
G
L
S
F
P
A
V
C
Zebra Danio
Brachydanio rerio
XP_694050
1122
127734
K497
H
I
R
L
E
E
S
K
F
F
G
E
Y
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95V25
1140
129511
Q491
R
V
I
V
Q
L
M
Q
Y
H
N
K
A
Y
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
21
67.4
N.A.
71.9
96.9
N.A.
36.3
76.7
20.1
76.4
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
100
97.8
41
76.6
N.A.
81.4
98.2
N.A.
41.2
84.5
38.7
85.1
N.A.
N.A.
N.A.
40.5
N.A.
P-Site Identity:
100
100
13.3
53.3
N.A.
60
100
N.A.
0
60
0
73.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
33.3
73.3
N.A.
73.3
100
N.A.
0
73.3
13.3
80
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
28
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
37
37
0
0
0
0
0
64
0
55
0
% E
% Phe:
0
0
0
0
0
10
0
0
64
64
10
0
0
0
0
% F
% Gly:
0
0
0
0
28
0
0
10
0
0
10
0
0
0
64
% G
% His:
64
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% H
% Ile:
0
64
10
0
0
10
0
10
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
37
10
0
0
10
0
10
0
% K
% Leu:
0
10
0
37
0
10
0
0
10
0
0
0
0
0
10
% L
% Met:
0
0
10
28
0
0
10
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
0
% Q
% Arg:
10
0
37
10
0
0
0
0
0
0
19
0
0
0
0
% R
% Ser:
0
0
10
10
0
0
73
0
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
28
0
0
0
0
0
0
0
% T
% Val:
0
19
28
10
10
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
0
10
0
64
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _