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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNT2 All Species: 27.27
Human Site: Y359 Identified Species: 60
UniProt: Q6UVM3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UVM3 NP_940905.2 1135 130501 Y359 M W S Q R V I Y L Q G S A L K
Chimpanzee Pan troglodytes XP_514073 1111 127635 Y359 M W S Q R V I Y L Q G S A L K
Rhesus Macaque Macaca mulatta O18867 1151 128915 G349 M V F F I L G G L A M F A S Y
Dog Lupus familis XP_548379 1319 147753 Y501 L W S Q R V I Y L Q G S A L K
Cat Felis silvestris
Mouse Mus musculus Q6ZPR4 1224 138087 Y398 L W S Q R V I Y L Q G S A L K
Rat Rattus norvegicus Q6UVM4 1142 131082 Y359 M W S Q R V I Y L Q G S A L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517416 550 62297
Chicken Gallus gallus Q8QFV0 1201 137224 Y410 L W S Q R V I Y L Q G S A L K
Frog Xenopus laevis Q90ZC7 1196 134483 F433 K H F T Q V E F Y Q G S V L N
Zebra Danio Brachydanio rerio XP_694050 1122 127734 Y357 L W A Q R V I Y L Q G S A L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95V25 1140 129511 A342 F F I L F G L A M F A S Y V P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 21 67.4 N.A. 71.9 96.9 N.A. 36.3 76.7 20.1 76.4 N.A. N.A. N.A. 20.2 N.A.
Protein Similarity: 100 97.8 41 76.6 N.A. 81.4 98.2 N.A. 41.2 84.5 38.7 85.1 N.A. N.A. N.A. 40.5 N.A.
P-Site Identity: 100 100 20 93.3 N.A. 93.3 100 N.A. 0 93.3 33.3 86.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 0 100 46.6 100 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 10 0 10 10 0 73 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 10 10 19 10 10 0 0 10 0 10 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 10 10 10 0 0 73 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 10 0 64 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 64 % K
% Leu: 37 0 0 10 0 10 10 0 73 0 0 0 0 73 0 % L
% Met: 37 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 64 10 0 0 0 0 73 0 0 0 0 0 % Q
% Arg: 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 55 0 0 0 0 0 0 0 0 82 0 10 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 73 0 0 0 0 0 0 10 10 0 % V
% Trp: 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 64 10 0 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _