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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP20A1 All Species: 16.67
Human Site: S112 Identified Species: 30.56
UniProt: Q6UW02 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UW02 NP_803882.1 462 52432 S112 K S L L R Y Q S G G G S V S E
Chimpanzee Pan troglodytes Q8HYN1 508 57365 A133 R L A M A T F A L F K D G D Q
Rhesus Macaque Macaca mulatta XP_001105388 458 51229 R112 P D P E R I Q R L R R L M V A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BKE6 462 52131 S112 K S L L G Y Q S G G G S A G E
Rat Rattus norvegicus Q6P7D4 462 51979 S112 K S L L G Y R S G A G S G S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506190 262 29719
Chicken Gallus gallus XP_426572 463 52409 S112 K S F L R Y Q S S L N G D A G
Frog Xenopus laevis NP_001079548 463 52021 S112 K S L L G Y Q S G V I G E A A
Zebra Danio Brachydanio rerio NP_998497 462 51647 S112 K S L L G Y Q S G S G V G L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXY0 495 57171 L113 P W L G K G L L T N G G E S W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792896 231 25756
Poplar Tree Populus trichocarpa XP_002300926 460 52070 S110 R L I G E P L S V D G L K T Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65790 500 57537 R126 D H W R N L R R I C S Q E I L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.2 60.6 N.A. N.A. 83.1 81.8 N.A. 42.6 73.6 73.2 63.8 N.A. 21 N.A. N.A. 23.1
Protein Similarity: 100 42.7 65.8 N.A. N.A. 90.6 91.1 N.A. 50.6 88.7 88.3 81.5 N.A. 38.7 N.A. N.A. 36.3
P-Site Identity: 100 0 13.3 N.A. N.A. 80 73.3 N.A. 0 46.6 53.3 60 N.A. 20 N.A. N.A. 0
P-Site Similarity: 100 26.6 20 N.A. N.A. 80 80 N.A. 0 53.3 60 60 N.A. 26.6 N.A. N.A. 0
Percent
Protein Identity: 23.8 N.A. N.A. 22.4 N.A. N.A.
Protein Similarity: 42.8 N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 0 0 8 0 8 0 0 8 16 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 0 8 0 8 8 8 0 % D
% Glu: 0 0 0 8 8 0 0 0 0 0 0 0 24 0 24 % E
% Phe: 0 0 8 0 0 0 8 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 16 31 8 0 0 39 16 47 24 24 8 8 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 8 0 0 8 0 8 0 0 8 0 % I
% Lys: 47 0 0 0 8 0 0 0 0 0 8 0 8 0 0 % K
% Leu: 0 16 47 47 0 8 16 8 16 8 0 16 0 8 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 8 8 0 0 0 0 % N
% Pro: 16 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 47 0 0 0 0 8 0 0 8 % Q
% Arg: 16 0 0 8 24 0 16 16 0 8 8 0 0 0 0 % R
% Ser: 0 47 0 0 0 0 0 54 8 8 8 24 0 24 0 % S
% Thr: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 8 % T
% Val: 0 0 0 0 0 0 0 0 8 8 0 8 8 8 0 % V
% Trp: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 47 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _