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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP20A1 All Species: 24.55
Human Site: S449 Identified Species: 45
UniProt: Q6UW02 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UW02 NP_803882.1 462 52432 S449 T K Y E L V T S S R E E A W I
Chimpanzee Pan troglodytes Q8HYN1 508 57365 V482 S L E G I P K V V F L I D S F
Rhesus Macaque Macaca mulatta XP_001105388 458 51229 S445 T K Y E L V T S S R E E A W I
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BKE6 462 52131 S449 M K Y E L V T S A R E E A W I
Rat Rattus norvegicus Q6P7D4 462 51979 S449 M K Y E L V T S C R E E T W I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506190 262 29719 P250 K Y E L V T S P K E E A W I T
Chicken Gallus gallus XP_426572 463 52409 S450 T K Y E L V T S P K E E A W I
Frog Xenopus laevis NP_001079548 463 52021 S450 T K Y E L V T S P K E E A W I
Zebra Danio Brachydanio rerio NP_998497 462 51647 T449 A R Y E L V T T P K D D T W I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXY0 495 57171 K476 P L A E L V T K S G N G I R L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792896 231 25756 E219 L D G N M P D E G S N R V K T
Poplar Tree Populus trichocarpa XP_002300926 460 52070 M448 V Q P T L V R M P R N K Y P V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65790 500 57537 G478 M S E S T G L G M R K M D P L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.2 60.6 N.A. N.A. 83.1 81.8 N.A. 42.6 73.6 73.2 63.8 N.A. 21 N.A. N.A. 23.1
Protein Similarity: 100 42.7 65.8 N.A. N.A. 90.6 91.1 N.A. 50.6 88.7 88.3 81.5 N.A. 38.7 N.A. N.A. 36.3
P-Site Identity: 100 0 100 N.A. N.A. 86.6 80 N.A. 6.6 86.6 86.6 46.6 N.A. 33.3 N.A. N.A. 0
P-Site Similarity: 100 13.3 100 N.A. N.A. 93.3 80 N.A. 20 93.3 93.3 80 N.A. 40 N.A. N.A. 6.6
Percent
Protein Identity: 23.8 N.A. N.A. 22.4 N.A. N.A.
Protein Similarity: 42.8 N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: 20 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 0 0 0 8 0 0 8 39 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 8 0 0 0 8 8 16 0 0 % D
% Glu: 0 0 24 62 0 0 0 8 0 8 54 47 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % F
% Gly: 0 0 8 8 0 8 0 8 8 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 8 8 8 54 % I
% Lys: 8 47 0 0 0 0 8 8 8 24 8 8 0 8 0 % K
% Leu: 8 16 0 8 70 0 8 0 0 0 8 0 0 0 16 % L
% Met: 24 0 0 0 8 0 0 8 8 0 0 8 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 24 0 0 0 0 % N
% Pro: 8 0 8 0 0 16 0 8 31 0 0 0 0 16 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 8 0 0 47 0 8 0 8 0 % R
% Ser: 8 8 0 8 0 0 8 47 24 8 0 0 0 8 0 % S
% Thr: 31 0 0 8 8 8 62 8 0 0 0 0 16 0 16 % T
% Val: 8 0 0 0 8 70 0 8 8 0 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 54 0 % W
% Tyr: 0 8 54 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _