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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP20A1 All Species: 10.3
Human Site: T159 Identified Species: 18.89
UniProt: Q6UW02 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UW02 NP_803882.1 462 52432 T159 K W L S Y P E T Q H V P L S Q
Chimpanzee Pan troglodytes Q8HYN1 508 57365 S180 V A V T N V I S L I C F N T S
Rhesus Macaque Macaca mulatta XP_001105388 458 51229 L159 E G S P L G E L H R C I R E G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BKE6 462 52131 T159 K W L S Y P E T Q H I P L S Q
Rat Rattus norvegicus Q6P7D4 462 51979 T159 K W L S Y P E T Q H I P L S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506190 262 29719
Chicken Gallus gallus XP_426572 463 52409 E159 A K W L S L P E A Q H I P L C
Frog Xenopus laevis NP_001079548 463 52021 Q159 A K W G T Y P Q S Q H V P L C
Zebra Danio Brachydanio rerio NP_998497 462 51647 K159 D K W A S Y P K S Q H T P L C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXY0 495 57171 G160 R L R T K A N G E S F D I Y P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792896 231 25756
Poplar Tree Populus trichocarpa XP_002300926 460 52070 L157 L L N Q K R L L P T R F T L K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65790 500 57537 E173 S N D F T H I E L E P L L S D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.2 60.6 N.A. N.A. 83.1 81.8 N.A. 42.6 73.6 73.2 63.8 N.A. 21 N.A. N.A. 23.1
Protein Similarity: 100 42.7 65.8 N.A. N.A. 90.6 91.1 N.A. 50.6 88.7 88.3 81.5 N.A. 38.7 N.A. N.A. 36.3
P-Site Identity: 100 0 6.6 N.A. N.A. 93.3 93.3 N.A. 0 0 0 0 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 26.6 13.3 N.A. N.A. 100 100 N.A. 0 0 0 6.6 N.A. 26.6 N.A. N.A. 0
Percent
Protein Identity: 23.8 N.A. N.A. 22.4 N.A. N.A.
Protein Similarity: 42.8 N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 8 0 8 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 24 % C
% Asp: 8 0 8 0 0 0 0 0 0 0 0 8 0 0 8 % D
% Glu: 8 0 0 0 0 0 31 16 8 8 0 0 0 8 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 8 16 0 0 0 % F
% Gly: 0 8 0 8 0 8 0 8 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 8 0 0 8 24 24 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 16 0 0 8 16 16 8 0 0 % I
% Lys: 24 24 0 0 16 0 0 8 0 0 0 0 0 0 8 % K
% Leu: 8 16 24 8 8 8 8 16 16 0 0 8 31 31 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 8 0 8 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 8 0 24 24 0 8 0 8 24 24 0 8 % P
% Gln: 0 0 0 8 0 0 0 8 24 24 0 0 0 0 24 % Q
% Arg: 8 0 8 0 0 8 0 0 0 8 8 0 8 0 0 % R
% Ser: 8 0 8 24 16 0 0 8 16 8 0 0 0 31 8 % S
% Thr: 0 0 0 16 16 0 0 24 0 8 0 8 8 8 0 % T
% Val: 8 0 8 0 0 8 0 0 0 0 8 8 0 0 0 % V
% Trp: 0 24 24 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 24 16 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _