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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPESP1 All Species: 11.82
Human Site: S22 Identified Species: 65
UniProt: Q6UW49 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UW49 NP_663633.1 350 39003 S22 S S V P A Y P S I T V T P D E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001084797 352 39407 S22 S S V P A Y P S I T V S P D E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9D5A0 399 44683 T21 S S L L A Y P T I T V L P D E
Rat Rattus norvegicus A0JPP4 409 45861 T22 S S F L A Y P T A T V L P D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515992 351 39214 N16 K T V K H F V N V L Q E M M R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 92 N.A. N.A. 45.8 44.9 N.A. 26.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 94.3 N.A. N.A. 64.1 60.3 N.A. 44.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 N.A. N.A. 73.3 66.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 N.A. N.A. 86.6 73.3 N.A. 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 80 0 0 0 20 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 80 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 80 % E
% Phe: 0 0 20 0 0 20 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 % I
% Lys: 20 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 20 40 0 0 0 0 0 20 0 40 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 20 20 0 % M
% Asn: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 40 0 0 80 0 0 0 0 0 80 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % R
% Ser: 80 80 0 0 0 0 0 40 0 0 0 20 0 0 0 % S
% Thr: 0 20 0 0 0 0 0 40 0 80 0 20 0 0 0 % T
% Val: 0 0 60 0 0 0 20 0 20 0 80 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _