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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM205
All Species:
18.18
Human Site:
Y140
Identified Species:
40
UniProt:
Q6UW68
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UW68
NP_001138888.1
189
21198
Y140
S
H
Q
G
P
D
P
Y
R
Q
L
R
E
K
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104963
189
21107
Y140
S
H
Q
G
P
D
P
Y
R
Q
L
R
E
K
D
Dog
Lupus familis
XP_533912
189
21127
Y140
S
H
Q
G
P
D
P
Y
R
Q
L
R
G
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91XE8
189
21161
Y140
N
F
Q
G
P
D
P
Y
R
Q
L
R
D
K
D
Rat
Rattus norvegicus
NP_001100274
189
21166
Y140
S
L
Q
G
P
D
P
Y
R
Q
L
R
E
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516741
186
20857
K138
S
S
N
Q
G
A
Y
K
Q
L
R
E
K
D
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GPW4
188
21158
Q140
S
A
N
K
E
G
Y
Q
L
L
Q
E
K
D
P
Zebra Danio
Brachydanio rerio
A1L2F6
188
21282
T140
S
S
N
R
E
G
Y
T
K
L
R
E
Q
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002302753
209
23222
N161
T
E
V
G
W
S
K
N
R
E
V
A
K
A
N
Maize
Zea mays
NP_001143919
209
22657
N161
E
E
V
G
W
S
K
N
Q
Q
V
A
K
S
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567130
213
23563
N165
D
E
V
G
W
S
K
N
R
E
K
A
K
S
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
88.8
N.A.
79.3
83
N.A.
59.2
N.A.
51.3
43.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
98.9
93.6
N.A.
88.8
88.3
N.A.
71.9
N.A.
68.2
61.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
80
93.3
N.A.
6.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
20
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.5
29.1
N.A.
30.5
N.A.
N.A.
Protein Similarity:
45.4
45.4
N.A.
44.1
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
46.6
40
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
0
28
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
46
0
0
0
0
0
0
10
28
46
% D
% Glu:
10
28
0
0
19
0
0
0
0
19
0
28
28
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
73
10
19
0
0
0
0
0
0
10
0
0
% G
% His:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
0
28
10
10
0
10
0
46
37
0
% K
% Leu:
0
10
0
0
0
0
0
0
10
28
46
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
28
0
0
0
0
28
0
0
0
0
0
0
19
% N
% Pro:
0
0
0
0
46
0
46
0
0
0
0
0
0
0
28
% P
% Gln:
0
0
46
10
0
0
0
10
19
55
10
0
10
10
0
% Q
% Arg:
0
0
0
10
0
0
0
0
64
0
19
46
0
0
0
% R
% Ser:
64
19
0
0
0
28
0
0
0
0
0
0
0
19
0
% S
% Thr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
28
0
0
0
0
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
28
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
28
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _