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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPGN All Species: 5.76
Human Site: S148 Identified Species: 15.83
UniProt: Q6UW88 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UW88 NP_001013460.1 154 17091 S148 K S P Y N V C S G E R R P L _
Chimpanzee Pan troglodytes XP_001155366 154 17072 S148 K S P Y N V C S G E R R P L _
Rhesus Macaque Macaca mulatta P55244 121 13164
Dog Lupus familis XP_854753 362 39070 S210 E L G Y P P R S S T T C A V S
Cat Felis silvestris
Mouse Mus musculus Q924X1 152 16781
Rat Rattus norvegicus P01134 159 16942 K147 E K P S A L L K G R T A C C H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511092 225 24299
Chicken Gallus gallus Q5EG71 151 17011
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001344391 148 16361
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 24 33.4 N.A. 79.2 25.7 N.A. 48 59.7 N.A. 30.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 42.2 35 N.A. 86.3 44 N.A. 56 70.7 N.A. 49.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 13.3 N.A. 0 13.3 N.A. 0 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 26.6 N.A. 0 26.6 N.A. 0 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 0 0 0 0 0 12 12 0 0 % A
% Cys: 0 0 0 0 0 0 23 0 0 0 0 12 12 12 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 23 0 0 0 0 0 0 0 0 23 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 12 0 0 0 0 0 34 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 23 12 0 0 0 0 0 12 0 0 0 0 0 0 0 % K
% Leu: 0 12 0 0 0 12 12 0 0 0 0 0 0 23 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 34 0 12 12 0 0 0 0 0 0 23 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 12 0 0 12 23 23 0 0 0 % R
% Ser: 0 23 0 12 0 0 0 34 12 0 0 0 0 0 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 12 23 0 0 0 0 % T
% Val: 0 0 0 0 0 23 0 0 0 0 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % _