KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM55D
All Species:
16.97
Human Site:
T474
Identified Species:
46.67
UniProt:
Q6UWF7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWF7
NP_001071107.1
544
62263
T474
D
T
M
V
I
I
K
T
E
N
I
R
E
M
Y
Chimpanzee
Pan troglodytes
XP_001151271
544
62170
T474
D
T
M
V
I
I
K
T
E
N
I
R
E
M
Y
Rhesus Macaque
Macaca mulatta
XP_001088696
544
62243
T474
D
T
M
V
I
I
K
T
E
N
I
R
E
M
Y
Dog
Lupus familis
XP_853868
592
67219
A522
D
T
M
V
I
I
K
A
E
N
I
R
E
M
H
Cat
Felis silvestris
Mouse
Mus musculus
Q52KP5
543
61533
T473
D
T
V
V
V
L
K
T
E
N
T
R
E
L
N
Rat
Rattus norvegicus
Q5XI89
542
61597
T472
D
T
L
V
V
L
K
T
E
N
T
R
E
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505448
503
57319
M439
K
T
E
N
T
R
E
M
M
A
E
P
E
R
F
Chicken
Gallus gallus
XP_416618
561
64229
A486
T
L
I
V
I
R
T
A
N
V
Q
E
L
G
P
Frog
Xenopus laevis
NP_001088614
530
61310
E459
S
T
K
V
I
I
K
E
E
N
A
R
D
M
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.2
70.9
N.A.
72.9
72.4
N.A.
54.9
30.6
43.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97.2
80
N.A.
84.9
84.9
N.A.
69.4
52.4
63.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
60
60
N.A.
13.3
13.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
26.6
20
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
23
0
12
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% D
% Glu:
0
0
12
0
0
0
12
12
78
0
12
12
78
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
12
0
67
56
0
0
0
0
45
0
0
0
0
% I
% Lys:
12
0
12
0
0
0
78
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
12
0
0
23
0
0
0
0
0
0
12
23
0
% L
% Met:
0
0
45
0
0
0
0
12
12
0
0
0
0
56
0
% M
% Asn:
0
0
0
12
0
0
0
0
12
78
0
0
0
0
23
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
23
0
0
0
0
0
78
0
12
0
% R
% Ser:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
12
89
0
0
12
0
12
56
0
0
23
0
0
0
0
% T
% Val:
0
0
12
89
23
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _