KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCO3
All Species:
31.82
Human Site:
Y125
Identified Species:
77.78
UniProt:
Q6UWJ1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWJ1
NP_060375.4
677
75598
Y125
Q
R
A
L
Q
G
D
Y
K
D
V
V
N
M
K
Chimpanzee
Pan troglodytes
XP_509748
677
75582
Y125
Q
R
A
L
Q
G
D
Y
K
D
V
V
N
M
K
Rhesus Macaque
Macaca mulatta
XP_001090544
672
75516
Y125
Q
R
A
L
Q
G
D
Y
K
D
V
V
N
M
K
Dog
Lupus familis
XP_848475
677
75806
Y125
Q
R
A
L
Q
G
D
Y
R
D
V
V
N
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH01
678
75885
Y125
Q
R
A
L
Q
G
D
Y
R
D
V
V
N
M
K
Rat
Rattus norvegicus
NP_001129329
678
75705
Y125
Q
R
A
L
Q
G
D
Y
R
D
V
V
N
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515113
677
75773
Y125
Q
R
A
L
Q
G
D
Y
K
D
V
V
N
M
K
Chicken
Gallus gallus
XP_001233181
678
75907
Y126
Q
R
A
L
Q
G
D
Y
K
D
V
V
N
M
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002660366
597
66583
E81
I
H
T
L
E
V
F
E
R
E
L
N
E
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_849990
592
64231
R76
S
F
A
D
M
I
D
R
A
L
E
K
E
F
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
89.2
87.5
N.A.
89.3
88.9
N.A.
87.3
87.4
N.A.
62
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
92.1
93.5
N.A.
94.2
93.2
N.A.
93.9
92.6
N.A.
75.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
100
100
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
90
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
90
0
0
80
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
10
0
10
10
0
20
0
10
% E
% Phe:
0
10
0
0
0
0
10
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
50
0
0
10
0
0
80
% K
% Leu:
0
0
0
90
0
0
0
0
0
10
10
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
80
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
80
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
80
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
80
0
0
0
0
0
10
40
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
80
80
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _