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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCTL
All Species:
20.61
Human Site:
Y493
Identified Species:
50.37
UniProt:
Q6UWM7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWM7
NP_997221.2
567
65088
Y493
Y
P
K
A
S
V
Q
Y
Y
K
K
I
I
I
A
Chimpanzee
Pan troglodytes
XP_001174693
567
65052
Y493
Y
P
K
A
S
V
Q
Y
Y
K
K
I
I
I
A
Rhesus Macaque
Macaca mulatta
XP_001110267
567
64827
Y493
Y
P
K
A
S
V
Q
Y
Y
K
K
I
I
I
A
Dog
Lupus familis
XP_544736
646
72999
Y572
Y
P
K
A
S
V
Q
Y
Y
E
K
I
I
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1F9
566
64807
Y492
Y
P
K
A
S
V
Q
Y
Y
K
E
I
I
T
A
Rat
Rattus norvegicus
NP_001101628
370
42887
D299
Y
T
S
R
S
L
L
D
K
F
E
W
E
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001106299
607
69234
Y512
I
P
K
K
S
T
K
Y
Y
R
S
I
I
L
C
Zebra Danio
Brachydanio rerio
NP_001093484
561
64853
F487
Y
P
K
A
S
V
Q
F
Y
K
R
I
I
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792744
548
62078
G477
E
G
Y
T
E
R
F
G
M
V
Y
I
D
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIW4
490
56058
A419
D
Y
F
K
S
Y
L
A
N
V
S
Q
A
I
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.8
80.1
N.A.
83.5
55.7
N.A.
N.A.
N.A.
42
68.7
N.A.
N.A.
N.A.
N.A.
46.3
Protein Similarity:
100
99.6
97.8
85.1
N.A.
90.4
59.4
N.A.
N.A.
N.A.
59.1
83.7
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
100
100
86.6
N.A.
86.6
13.3
N.A.
N.A.
N.A.
46.6
73.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
N.A.
N.A.
66.6
93.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
60
0
0
0
10
0
0
0
0
10
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% D
% Glu:
10
0
0
0
10
0
0
0
0
10
20
0
10
0
10
% E
% Phe:
0
0
10
0
0
0
10
10
0
10
0
0
0
10
0
% F
% Gly:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
80
70
40
0
% I
% Lys:
0
0
70
20
0
0
10
0
10
50
40
0
0
10
0
% K
% Leu:
0
0
0
0
0
10
20
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
60
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
10
0
10
0
0
0
10
10
0
0
0
0
% R
% Ser:
0
0
10
0
90
0
0
0
0
0
20
0
0
0
20
% S
% Thr:
0
10
0
10
0
10
0
0
0
0
0
0
0
20
0
% T
% Val:
0
0
0
0
0
60
0
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
70
10
10
0
0
10
0
60
70
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _