Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCLAT1 All Species: 5.45
Human Site: S215 Identified Species: 8.57
UniProt: Q6UWP7 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UWP7 NP_001002257.1 414 48920 S215 T E N S K S R S N A F A E K N
Chimpanzee Pan troglodytes XP_001163263 414 48844 S215 T E N S K S R S N A F A E K N
Rhesus Macaque Macaca mulatta XP_001104425 376 44573 F200 L H P R T T G F T F V V D R L
Dog Lupus familis XP_540138 376 44590 F200 L H P R T T G F T F V V D R L
Cat Felis silvestris
Mouse Mus musculus Q3UN02 376 44381 F200 L H P R T T G F T F V V D R L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510123 376 44599 F200 L H P R T T G F T F V V E R L
Chicken Gallus gallus Q5F3X0 378 44430 F202 P R T T G F T F V V E C L R E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NYV8 388 44727 N212 D T L R G G D N L D A V H D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001123248 373 43793 K197 T D L T K S S K E K S N K Y A
Nematode Worm Caenorhab. elegans NP_504643 344 40052 G168 Q I L L F A E G T D K G E R A
Sea Urchin Strong. purpuratus XP_782691 375 43561 T199 K Y V L H P H T T G F S F T L
Poplar Tree Populus trichocarpa XP_002327077 372 42900 C196 T D F S E E K C Q K S Q R F A
Maize Zea mays Q41745 374 42553 N198 Q G L P A P R N V L I P R T K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L4Y2 378 43045 A202 K R S Q K F A A E V G L P A L
Baker's Yeast Sacchar. cerevisiae Q12185 396 45920 I213 S I A A Y N L I M F P E G T N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 88.8 84.5 N.A. 80.9 N.A. N.A. 73.4 69.3 N.A. 57.2 N.A. N.A. 34.5 34 35.2
Protein Similarity: 100 99.7 89.8 88.1 N.A. 85.9 N.A. N.A. 82.6 80.1 N.A. 71.9 N.A. N.A. 55 52.1 52.9
P-Site Identity: 100 100 0 0 N.A. 0 N.A. N.A. 6.6 0 N.A. 0 N.A. N.A. 20 6.6 6.6
P-Site Similarity: 100 100 20 20 N.A. 20 N.A. N.A. 20 13.3 N.A. 6.6 N.A. N.A. 40 20 20
Percent
Protein Identity: 28.2 24.4 N.A. 28 20.7 N.A.
Protein Similarity: 44.9 39.8 N.A. 45.1 34.7 N.A.
P-Site Identity: 13.3 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: 33.3 13.3 N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 7 7 7 7 0 14 7 14 0 7 20 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % C
% Asp: 7 14 0 0 0 0 7 0 0 14 0 0 20 7 0 % D
% Glu: 0 14 0 0 7 7 7 0 14 0 7 7 27 0 7 % E
% Phe: 0 0 7 0 7 14 0 34 0 34 20 0 7 7 0 % F
% Gly: 0 7 0 0 14 7 27 7 0 7 7 7 7 0 0 % G
% His: 0 27 0 0 7 0 7 0 0 0 0 0 7 0 0 % H
% Ile: 0 14 0 0 0 0 0 7 0 0 7 0 0 0 7 % I
% Lys: 14 0 0 0 27 0 7 7 0 14 7 0 7 14 7 % K
% Leu: 27 0 27 14 0 0 7 0 7 7 0 7 7 0 40 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 14 0 0 7 0 14 14 0 0 7 0 0 20 % N
% Pro: 7 0 27 7 0 14 0 0 0 0 7 7 7 0 0 % P
% Gln: 14 0 0 7 0 0 0 0 7 0 0 7 0 0 0 % Q
% Arg: 0 14 0 34 0 0 20 0 0 0 0 0 14 40 0 % R
% Ser: 7 0 7 20 0 20 7 14 0 0 14 7 0 0 0 % S
% Thr: 27 7 7 14 27 27 7 7 40 0 0 0 0 20 0 % T
% Val: 0 0 7 0 0 0 0 0 14 14 27 34 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _