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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCLAT1 All Species: 5.15
Human Site: Y227 Identified Species: 8.1
UniProt: Q6UWP7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UWP7 NP_001002257.1 414 48920 Y227 E K N G L Q K Y E Y V L H P R
Chimpanzee Pan troglodytes XP_001163263 414 48844 Y227 E K N G L Q K Y E Y V L H P R
Rhesus Macaque Macaca mulatta XP_001104425 376 44573 N212 D R L R E G K N L D A I H D I
Dog Lupus familis XP_540138 376 44590 N212 D R L R E G R N L D A V H D I
Cat Felis silvestris
Mouse Mus musculus Q3UN02 376 44381 N212 D R L R E G K N L D A V H D I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510123 376 44599 N212 E R L R E G R N L D A I H D I
Chicken Gallus gallus Q5F3X0 378 44430 D214 L R E G N N L D A I H D I T V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NYV8 388 44727 P224 H D I T V A Y P Q N I P Q T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001123248 373 43793 L209 K Y A M Q H V L P Q Y S F I L
Nematode Worm Caenorhab. elegans NP_504643 344 40052 D180 E R A T R L S D A F A D K N G
Sea Urchin Strong. purpuratus XP_782691 375 43561 Q211 F T L D Y L K Q M K K I D T V
Poplar Tree Populus trichocarpa XP_002327077 372 42900 L208 R F A S E V G L P V L A N V L
Maize Zea mays Q41745 374 42553 A210 R T K G F V S A V S I M R D F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L4Y2 378 43045 L214 P A L S N V L L P K T R G F G
Baker's Yeast Sacchar. cerevisiae Q12185 396 45920 T225 G T N L S L K T R E K S E A F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 88.8 84.5 N.A. 80.9 N.A. N.A. 73.4 69.3 N.A. 57.2 N.A. N.A. 34.5 34 35.2
Protein Similarity: 100 99.7 89.8 88.1 N.A. 85.9 N.A. N.A. 82.6 80.1 N.A. 71.9 N.A. N.A. 55 52.1 52.9
P-Site Identity: 100 100 13.3 6.6 N.A. 13.3 N.A. N.A. 13.3 6.6 N.A. 0 N.A. N.A. 0 6.6 6.6
P-Site Similarity: 100 100 33.3 33.3 N.A. 33.3 N.A. N.A. 33.3 13.3 N.A. 20 N.A. N.A. 6.6 20 13.3
Percent
Protein Identity: 28.2 24.4 N.A. 28 20.7 N.A.
Protein Similarity: 44.9 39.8 N.A. 45.1 34.7 N.A.
P-Site Identity: 0 6.6 N.A. 0 13.3 N.A.
P-Site Similarity: 13.3 20 N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 20 0 0 7 0 7 14 0 34 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 7 0 7 0 0 0 14 0 27 0 14 7 34 0 % D
% Glu: 27 0 7 0 34 0 0 0 14 7 0 0 7 0 7 % E
% Phe: 7 7 0 0 7 0 0 0 0 7 0 0 7 7 14 % F
% Gly: 7 0 0 27 0 27 7 0 0 0 0 0 7 0 14 % G
% His: 7 0 0 0 0 7 0 0 0 0 7 0 40 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 7 14 20 7 7 27 % I
% Lys: 7 14 7 0 0 0 40 0 0 14 14 0 7 0 0 % K
% Leu: 7 0 40 7 14 20 14 20 27 0 7 14 0 0 14 % L
% Met: 0 0 0 7 0 0 0 0 7 0 0 7 0 0 0 % M
% Asn: 0 0 20 0 14 7 0 27 0 7 0 0 7 7 0 % N
% Pro: 7 0 0 0 0 0 0 7 20 0 0 7 0 14 0 % P
% Gln: 0 0 0 0 7 14 0 7 7 7 0 0 7 0 0 % Q
% Arg: 14 40 0 27 7 0 14 0 7 0 0 7 7 0 14 % R
% Ser: 0 0 0 14 7 0 14 0 0 7 0 14 0 0 0 % S
% Thr: 0 20 0 14 0 0 0 7 0 0 7 0 0 20 0 % T
% Val: 0 0 0 0 7 20 7 0 7 7 14 14 0 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 7 14 0 14 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _