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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCLAT1 All Species: 5.76
Human Site: Y261 Identified Species: 9.05
UniProt: Q6UWP7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UWP7 NP_001002257.1 414 48920 Y261 V H D I T V A Y P H N I P Q S
Chimpanzee Pan troglodytes XP_001163263 414 48844 Y261 V H D I T V A Y P H N I P Q S
Rhesus Macaque Macaca mulatta XP_001104425 376 44573 E242 L R G D F P R E I H F H V H R
Dog Lupus familis XP_540138 376 44590 E242 L L G D F P K E I H F H V R R
Cat Felis silvestris
Mouse Mus musculus Q3UN02 376 44381 E242 L L G D F P K E I H F H V Q R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510123 376 44599 E242 L E G N F P K E I H F H I H R
Chicken Gallus gallus Q5F3X0 378 44430 H244 G N F P K E I H F H V Q R Y P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NYV8 388 44727 S254 V Q R F T V A S V P A G A A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001123248 373 43793 V239 Q A K Y L N A V Y D L T I A Y
Nematode Worm Caenorhab. elegans NP_504643 344 40052 K210 K F L M E L M K K E N Y I K Y
Sea Urchin Strong. purpuratus XP_782691 375 43561 N241 E I D F F R G N V P Q E M E F
Poplar Tree Populus trichocarpa XP_002327077 372 42900 D238 N S L D A V Y D V S I A Y K D
Maize Zea mays Q41745 374 42553 I240 P Q P T M L R I L K G Q S S V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L4Y2 378 43045 R244 L T I A Y K P R C P S F M D N
Baker's Yeast Sacchar. cerevisiae Q12185 396 45920 F256 P H S K G L K F A V E K L A P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 88.8 84.5 N.A. 80.9 N.A. N.A. 73.4 69.3 N.A. 57.2 N.A. N.A. 34.5 34 35.2
Protein Similarity: 100 99.7 89.8 88.1 N.A. 85.9 N.A. N.A. 82.6 80.1 N.A. 71.9 N.A. N.A. 55 52.1 52.9
P-Site Identity: 100 100 6.6 6.6 N.A. 13.3 N.A. N.A. 6.6 6.6 N.A. 26.6 N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: 100 100 13.3 20 N.A. 20 N.A. N.A. 13.3 20 N.A. 26.6 N.A. N.A. 6.6 26.6 13.3
Percent
Protein Identity: 28.2 24.4 N.A. 28 20.7 N.A.
Protein Similarity: 44.9 39.8 N.A. 45.1 34.7 N.A.
P-Site Identity: 6.6 0 N.A. 0 6.6 N.A.
P-Site Similarity: 13.3 6.6 N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 7 0 27 0 7 0 7 7 7 20 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 20 27 0 0 0 7 0 7 0 0 0 7 7 % D
% Glu: 7 7 0 0 7 7 0 27 0 7 7 7 0 7 0 % E
% Phe: 0 7 7 14 34 0 0 7 7 0 27 7 0 0 7 % F
% Gly: 7 0 27 0 7 0 7 0 0 0 7 7 0 0 7 % G
% His: 0 20 0 0 0 0 0 7 0 47 0 27 0 14 0 % H
% Ile: 0 7 7 14 0 0 7 7 27 0 7 14 20 0 0 % I
% Lys: 7 0 7 7 7 7 27 7 7 7 0 7 0 14 0 % K
% Leu: 34 14 14 0 7 20 0 0 7 0 7 0 7 0 0 % L
% Met: 0 0 0 7 7 0 7 0 0 0 0 0 14 0 0 % M
% Asn: 7 7 0 7 0 7 0 7 0 0 20 0 0 0 7 % N
% Pro: 14 0 7 7 0 27 7 0 14 20 0 0 14 0 14 % P
% Gln: 7 14 0 0 0 0 0 0 0 0 7 14 0 20 0 % Q
% Arg: 0 7 7 0 0 7 14 7 0 0 0 0 7 7 27 % R
% Ser: 0 7 7 0 0 0 0 7 0 7 7 0 7 7 14 % S
% Thr: 0 7 0 7 20 0 0 0 0 0 0 7 0 0 0 % T
% Val: 20 0 0 0 0 27 0 7 20 7 7 0 20 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 7 0 7 14 7 0 0 7 7 7 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _