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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCLAT1
All Species:
5.76
Human Site:
Y399
Identified Species:
9.05
UniProt:
Q6UWP7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWP7
NP_001002257.1
414
48920
Y399
E
I
I
E
L
A
C
Y
R
L
L
H
K
Q
P
Chimpanzee
Pan troglodytes
XP_001163263
414
48844
Y399
E
I
I
E
L
A
C
Y
Q
L
L
H
K
Q
P
Rhesus Macaque
Macaca mulatta
XP_001104425
376
44573
R362
I
I
E
L
A
C
Y
R
L
L
H
K
Q
P
H
Dog
Lupus familis
XP_540138
376
44590
R362
I
I
E
L
A
C
Y
R
F
F
H
K
Q
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3UN02
376
44381
R362
I
I
E
L
A
C
Y
R
F
L
H
K
H
P
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510123
376
44599
R362
F
I
E
L
A
C
Y
R
F
L
A
K
R
Q
S
Chicken
Gallus gallus
Q5F3X0
378
44430
F364
E
L
A
C
H
Q
Y
F
K
K
Q
Q
K
H
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NYV8
388
44727
A374
G
L
E
L
M
E
L
A
C
H
R
Y
W
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001123248
373
43793
A359
I
H
S
A
F
F
I
A
L
S
F
F
T
T
G
Nematode Worm
Caenorhab. elegans
NP_504643
344
40052
V330
A
I
Y
S
L
L
W
V
K
V
I
N
R
F
Y
Sea Urchin
Strong. purpuratus
XP_782691
375
43561
S361
A
D
N
L
A
I
S
S
F
N
F
T
Q
D
I
Poplar Tree
Populus trichocarpa
XP_002327077
372
42900
A358
A
C
A
Y
L
A
S
A
T
H
F
K
F
R
P
Maize
Zea mays
Q41745
374
42553
R360
I
M
F
S
Q
A
E
R
S
S
S
A
R
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L4Y2
378
43045
S364
T
Y
Y
K
F
Q
P
S
P
G
C
F
R
E
D
Baker's Yeast
Sacchar. cerevisiae
Q12185
396
45920
F382
R
I
L
S
Y
Y
G
F
F
A
F
L
I
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
88.8
84.5
N.A.
80.9
N.A.
N.A.
73.4
69.3
N.A.
57.2
N.A.
N.A.
34.5
34
35.2
Protein Similarity:
100
99.7
89.8
88.1
N.A.
85.9
N.A.
N.A.
82.6
80.1
N.A.
71.9
N.A.
N.A.
55
52.1
52.9
P-Site Identity:
100
93.3
13.3
6.6
N.A.
13.3
N.A.
N.A.
20
13.3
N.A.
0
N.A.
N.A.
0
13.3
0
P-Site Similarity:
100
100
20
13.3
N.A.
13.3
N.A.
N.A.
26.6
33.3
N.A.
20
N.A.
N.A.
0
46.6
6.6
Percent
Protein Identity:
28.2
24.4
N.A.
28
20.7
N.A.
Protein Similarity:
44.9
39.8
N.A.
45.1
34.7
N.A.
P-Site Identity:
20
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
26.6
20
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
14
7
34
27
0
20
0
7
7
7
0
7
7
% A
% Cys:
0
7
0
7
0
27
14
0
7
0
7
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
14
% D
% Glu:
20
0
34
14
0
7
7
0
0
0
0
0
0
7
0
% E
% Phe:
7
0
7
0
14
7
0
14
34
7
27
14
7
7
0
% F
% Gly:
7
0
0
0
0
0
7
0
0
7
0
0
0
0
7
% G
% His:
0
7
0
0
7
0
0
0
0
14
20
14
7
7
20
% H
% Ile:
34
54
14
0
0
7
7
0
0
0
7
0
7
0
7
% I
% Lys:
0
0
0
7
0
0
0
0
14
7
0
34
20
0
0
% K
% Leu:
0
14
7
40
27
7
7
0
14
34
14
7
0
7
0
% L
% Met:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
7
0
0
0
0
20
20
% P
% Gln:
0
0
0
0
7
14
0
0
7
0
7
7
20
20
0
% Q
% Arg:
7
0
0
0
0
0
0
34
7
0
7
0
27
7
7
% R
% Ser:
0
0
7
20
0
0
14
14
7
14
7
0
0
7
7
% S
% Thr:
7
0
0
0
0
0
0
0
7
0
0
7
7
7
0
% T
% Val:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% W
% Tyr:
0
7
14
7
7
7
34
14
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _