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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENPP6
All Species:
20.61
Human Site:
T420
Identified Species:
45.33
UniProt:
Q6UWR7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWR7
NP_699174.1
440
50241
T420
M
L
K
G
R
A
S
T
A
P
P
V
W
P
S
Chimpanzee
Pan troglodytes
XP_517551
440
50241
T420
M
L
K
G
R
A
G
T
A
P
P
F
W
P
S
Rhesus Macaque
Macaca mulatta
XP_001082274
440
50341
T420
M
L
K
G
R
A
S
T
A
P
P
V
Q
P
S
Dog
Lupus familis
XP_532849
637
71308
S617
M
L
K
D
Q
A
S
S
A
L
S
V
Q
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGN3
440
50600
S420
M
L
K
G
Q
T
S
S
A
P
P
T
P
L
N
Rat
Rattus norvegicus
B0BND0
440
50683
S420
M
L
K
S
Q
T
S
S
S
P
S
I
P
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511525
784
89004
R715
M
L
E
T
V
I
P
R
V
P
S
T
T
A
H
Chicken
Gallus gallus
XP_420512
438
50532
R416
M
L
K
N
T
A
V
R
V
P
L
C
T
R
S
Frog
Xenopus laevis
Q6DDP3
441
51468
F420
M
L
R
S
S
S
G
F
P
T
T
L
H
L
I
Zebra Danio
Brachydanio rerio
Q5BKW7
438
50676
T418
M
M
R
S
S
A
A
T
A
G
A
S
L
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25353
742
84715
Q607
M
N
Q
L
R
E
P
Q
S
S
E
E
V
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.9
64.6
N.A.
86.1
86.5
N.A.
20.7
70.2
63.2
59
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.6
66.2
N.A.
91.8
92.2
N.A.
34.8
81.8
76.6
75.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
93.3
60
N.A.
53.3
40
N.A.
20
40
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
93.3
73.3
N.A.
73.3
73.3
N.A.
26.6
40
33.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
31.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
55
10
0
55
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
10
0
0
0
0
10
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
37
0
0
19
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
19
% I
% Lys:
0
0
64
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
82
0
10
0
0
0
0
0
10
10
10
10
19
0
% L
% Met:
100
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
19
% N
% Pro:
0
0
0
0
0
0
19
0
10
64
37
0
19
46
0
% P
% Gln:
0
0
10
0
28
0
0
10
0
0
0
0
19
0
0
% Q
% Arg:
0
0
19
0
37
0
0
19
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
28
19
10
46
28
19
10
28
10
0
0
55
% S
% Thr:
0
0
0
10
10
19
0
37
0
10
10
19
19
0
0
% T
% Val:
0
0
0
0
10
0
10
0
19
0
0
28
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _