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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLB1L
All Species:
17.88
Human Site:
T218
Identified Species:
32.78
UniProt:
Q6UWU2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWU2
NP_078782.3
654
74158
T218
E
K
I
L
L
F
T
T
D
G
P
E
G
L
K
Chimpanzee
Pan troglodytes
XP_526035
654
74191
T218
E
K
I
L
L
F
T
T
D
G
P
E
G
L
K
Rhesus Macaque
Macaca mulatta
XP_001098786
654
74062
T218
E
K
I
L
L
F
T
T
D
G
P
E
G
L
K
Dog
Lupus familis
XP_851411
651
73709
T217
D
R
I
L
L
F
T
T
D
G
P
E
G
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC60
646
73260
T214
D
K
I
L
L
F
T
T
D
G
P
H
G
L
R
Rat
Rattus norvegicus
Q5XIL5
631
72305
L230
N
R
G
I
V
E
L
L
L
T
S
D
N
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514897
656
73205
G218
V
V
L
F
T
T
D
G
A
N
K
N
F
L
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121284
645
72749
G218
V
I
L
F
T
T
D
G
S
A
L
Q
L
V
R
Zebra Danio
Brachydanio rerio
NP_001116328
629
71039
G217
V
I
L
F
T
T
D
G
N
T
D
K
E
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650142
637
71878
N213
G
Q
A
V
L
F
T
N
D
G
P
S
V
L
R
Honey Bee
Apis mellifera
XP_001121565
644
73067
G222
A
L
L
Y
T
T
D
G
S
N
M
N
M
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792349
657
74597
G205
V
V
L
F
T
T
D
G
P
G
D
H
L
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93Z24
697
78621
E255
T
T
D
G
G
T
K
E
T
L
D
K
G
T
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.7
85.1
N.A.
80.7
37.4
N.A.
48.4
N.A.
50.6
54.7
N.A.
41.9
41.7
N.A.
48.7
Protein Similarity:
100
99.5
98.4
92.3
N.A.
89.3
54.1
N.A.
64.6
N.A.
67.4
68.3
N.A.
58.4
57
N.A.
63
P-Site Identity:
100
100
100
80
N.A.
80
0
N.A.
13.3
N.A.
0
0
N.A.
46.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
20
N.A.
26.6
26.6
N.A.
66.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
0
0
0
39
0
47
0
24
8
0
0
0
% D
% Glu:
24
0
0
0
0
8
0
8
0
0
0
31
8
8
0
% E
% Phe:
0
0
0
31
0
47
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
8
8
0
0
39
0
54
0
0
47
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% H
% Ile:
0
16
39
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
31
0
0
0
0
8
0
0
0
8
16
0
0
31
% K
% Leu:
0
8
39
39
47
0
8
8
8
8
8
0
16
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% M
% Asn:
8
0
0
0
0
0
0
8
8
16
0
16
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
47
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% Q
% Arg:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
31
% R
% Ser:
0
0
0
0
0
0
0
0
16
0
8
8
0
0
16
% S
% Thr:
8
8
0
0
39
47
47
39
8
16
0
0
0
8
0
% T
% Val:
31
16
0
8
8
0
0
0
0
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _