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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENPP7
All Species:
0.91
Human Site:
T426
Identified Species:
2
UniProt:
Q6UWV6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWV6
NP_848638.2
458
51494
T426
L
P
P
D
G
R
P
T
L
L
P
K
G
R
S
Chimpanzee
Pan troglodytes
XP_001143218
474
54368
K418
I
L
L
P
G
S
V
K
P
A
E
Y
D
Q
E
Rhesus Macaque
Macaca mulatta
XP_001108871
607
67766
A575
L
P
P
D
G
R
P
A
L
P
L
H
G
R
S
Dog
Lupus familis
XP_850800
1017
110065
P669
R
P
V
S
T
P
P
P
T
L
Q
G
T
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQG7
477
54368
K421
T
L
L
L
G
S
D
K
P
G
E
D
E
Q
E
Rat
Rattus norvegicus
Q5EZ72
439
49818
L408
N
D
G
H
P
G
V
L
Q
P
M
L
R
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511525
784
89004
P729
H
P
N
A
S
V
K
P
R
I
S
E
Q
E
E
Chicken
Gallus gallus
XP_423912
437
49261
R405
D
G
S
L
E
V
T
R
P
M
L
R
S
S
A
Frog
Xenopus laevis
Q6AX80
452
51293
G409
I
Q
V
S
E
A
I
G
I
V
I
G
A
I
M
Zebra Danio
Brachydanio rerio
Q566N0
459
51584
G413
G
E
L
A
L
A
V
G
L
V
M
G
V
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188099
421
47502
S390
E
P
A
S
P
T
T
S
P
C
D
N
A
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.9
71.3
38.4
N.A.
35
78.5
N.A.
21
61.3
31.8
31.3
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
52.5
73.4
41.8
N.A.
53.2
86.4
N.A.
34.8
72.9
52.1
48.7
N.A.
N.A.
N.A.
N.A.
52.4
P-Site Identity:
100
6.6
73.3
26.6
N.A.
6.6
0
N.A.
6.6
0
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
73.3
26.6
N.A.
13.3
0
N.A.
20
20
20
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
19
0
19
0
10
0
10
0
0
19
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
10
0
19
0
0
10
0
0
0
10
10
10
0
0
% D
% Glu:
10
10
0
0
19
0
0
0
0
0
19
10
10
10
28
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
0
37
10
0
19
0
10
0
28
19
0
10
% G
% His:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
19
0
0
0
0
0
10
0
10
10
10
0
0
10
10
% I
% Lys:
0
0
0
0
0
0
10
19
0
0
0
10
0
0
0
% K
% Leu:
19
19
28
19
10
0
0
10
28
19
19
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
19
0
0
0
10
% M
% Asn:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
46
19
10
19
10
28
19
37
19
10
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
10
0
10
19
0
% Q
% Arg:
10
0
0
0
0
19
0
10
10
0
0
10
10
19
0
% R
% Ser:
0
0
10
28
10
19
0
10
0
0
10
0
10
37
28
% S
% Thr:
10
0
0
0
10
10
19
10
10
0
0
0
10
0
0
% T
% Val:
0
0
19
0
0
19
28
0
0
19
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _