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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENPP7
All Species:
15.45
Human Site:
Y109
Identified Species:
34
UniProt:
Q6UWV6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWV6
NP_848638.2
458
51494
Y109
T
S
K
V
K
L
P
Y
H
A
T
L
G
I
Q
Chimpanzee
Pan troglodytes
XP_001143218
474
54368
I108
F
S
L
D
H
M
N
I
Y
D
S
K
F
W
E
Rhesus Macaque
Macaca mulatta
XP_001108871
607
67766
Y258
T
S
R
V
K
L
P
Y
H
A
T
L
G
I
Q
Dog
Lupus familis
XP_850800
1017
110065
Y352
T
S
K
V
K
L
P
Y
H
A
T
L
G
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQG7
477
54368
I111
F
S
L
E
H
M
D
I
Y
D
S
K
F
W
E
Rat
Rattus norvegicus
Q5EZ72
439
49818
Y108
T
N
K
V
R
L
P
Y
H
A
T
L
G
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511525
784
89004
L416
I
L
N
Q
T
F
S
L
D
H
V
N
I
S
E
Chicken
Gallus gallus
XP_423912
437
49261
S108
G
V
K
L
P
Y
Y
S
T
Q
G
I
D
S
W
Frog
Xenopus laevis
Q6AX80
452
51293
S109
Q
V
F
H
M
N
D
S
H
S
K
W
W
D
E
Zebra Danio
Brachydanio rerio
Q566N0
459
51584
I110
V
A
K
K
H
F
S
I
K
N
D
S
D
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188099
421
47502
E94
E
W
F
D
T
G
A
E
P
V
W
V
T
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.9
71.3
38.4
N.A.
35
78.5
N.A.
21
61.3
31.8
31.3
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
52.5
73.4
41.8
N.A.
53.2
86.4
N.A.
34.8
72.9
52.1
48.7
N.A.
N.A.
N.A.
N.A.
52.4
P-Site Identity:
100
6.6
93.3
93.3
N.A.
6.6
86.6
N.A.
0
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
100
100
N.A.
33.3
100
N.A.
6.6
20
20
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
0
0
37
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
19
0
10
19
10
0
19
10
0
% D
% Glu:
10
0
0
10
0
0
0
10
0
0
0
0
0
0
37
% E
% Phe:
19
0
19
0
0
19
0
0
0
0
0
0
19
0
10
% F
% Gly:
10
0
0
0
0
10
0
0
0
0
10
0
37
0
0
% G
% His:
0
0
0
10
28
0
0
0
46
10
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
28
0
0
0
10
10
28
10
% I
% Lys:
0
0
46
10
28
0
0
0
10
0
10
19
0
0
0
% K
% Leu:
0
10
19
10
0
37
0
10
0
0
0
37
0
0
0
% L
% Met:
0
0
0
0
10
19
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
10
10
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
10
0
37
0
10
0
0
0
0
10
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
37
% Q
% Arg:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
46
0
0
0
0
19
19
0
10
19
10
0
19
0
% S
% Thr:
37
0
0
0
19
0
0
0
10
0
37
0
10
0
0
% T
% Val:
10
19
0
37
0
0
0
0
0
10
10
10
0
10
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
10
10
10
19
10
% W
% Tyr:
0
0
0
0
0
10
10
37
19
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _