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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENPP7 All Species: 18.79
Human Site: Y45 Identified Species: 41.33
UniProt: Q6UWV6 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UWV6 NP_848638.2 458 51494 Y45 F D G F R W N Y D Q D V D T P
Chimpanzee Pan troglodytes XP_001143218 474 54368 P44 W D Y L Y K V P T P H F H Y I
Rhesus Macaque Macaca mulatta XP_001108871 607 67766 Y194 F D G F R W N Y D Q D V D T P
Dog Lupus familis XP_850800 1017 110065 Y288 F D G F R W N Y D Q D V H T P
Cat Felis silvestris
Mouse Mus musculus Q9EQG7 477 54368 P47 W D Y L Y K V P T P H F H Y I
Rat Rattus norvegicus Q5EZ72 439 49818 Y44 F D G F R W N Y D Q D V E T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511525 784 89004 Y352 F D G F R W D Y I N K A P T P
Chicken Gallus gallus XP_423912 437 49261 Q44 G F R W D Y D Q D V D T P N L
Frog Xenopus laevis Q6AX80 452 51293 R45 F R A D Y L T R F P M P N L Q
Zebra Danio Brachydanio rerio Q566N0 459 51584 Y46 F D G F R A D Y L N K Y S F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188099 421 47502 G30 L K E V E R N G V K A S W M N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.9 71.3 38.4 N.A. 35 78.5 N.A. 21 61.3 31.8 31.3 N.A. N.A. N.A. N.A. 34.7
Protein Similarity: 100 52.5 73.4 41.8 N.A. 53.2 86.4 N.A. 34.8 72.9 52.1 48.7 N.A. N.A. N.A. N.A. 52.4
P-Site Identity: 100 6.6 100 93.3 N.A. 6.6 93.3 N.A. 60 13.3 6.6 46.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 93.3 N.A. 13.3 100 N.A. 66.6 33.3 13.3 53.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 0 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 73 0 10 10 0 28 0 46 0 46 0 19 0 0 % D
% Glu: 0 0 10 0 10 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 64 10 0 55 0 0 0 0 10 0 0 19 0 10 0 % F
% Gly: 10 0 55 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 19 0 28 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 19 % I
% Lys: 0 10 0 0 0 19 0 0 0 10 19 0 0 0 0 % K
% Leu: 10 0 0 19 0 10 0 0 10 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 46 0 0 19 0 0 10 10 10 % N
% Pro: 0 0 0 0 0 0 0 19 0 28 0 10 19 0 55 % P
% Gln: 0 0 0 0 0 0 0 10 0 37 0 0 0 0 10 % Q
% Arg: 0 10 10 0 55 10 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 19 0 0 10 0 46 0 % T
% Val: 0 0 0 10 0 0 19 0 10 10 0 37 0 0 0 % V
% Trp: 19 0 0 10 0 46 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 19 0 28 10 0 55 0 0 0 10 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _