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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CES3
All Species:
4.85
Human Site:
T39
Identified Species:
17.78
UniProt:
Q6UWW8
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWW8
NP_079198.2
571
62282
T39
A
Q
P
E
V
D
T
T
L
G
R
V
R
G
R
Chimpanzee
Pan troglodytes
XP_511224
571
62453
T39
D
Q
P
E
V
D
T
T
L
G
R
V
R
G
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546889
559
61595
H37
A
S
P
I
R
T
T
H
T
G
Q
V
R
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCU1
568
62988
P39
I
Q
P
E
V
D
T
P
L
G
R
V
R
G
R
Rat
Rattus norvegicus
P16303
565
62129
Y37
K
G
K
V
L
G
K
Y
V
N
L
E
G
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510356
585
64789
K50
R
Q
P
V
V
D
T
K
Y
G
K
V
Q
G
K
Chicken
Gallus gallus
XP_414148
561
62956
A37
A
E
P
E
V
T
I
A
H
G
R
L
R
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
46.5
N.A.
66.7
45.1
N.A.
44.2
44.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
N.A.
63.2
N.A.
79.8
62.7
N.A.
64
62
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
N.A.
46.6
N.A.
86.6
0
N.A.
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
53.3
N.A.
86.6
13.3
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
0
0
0
0
0
15
0
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
58
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
58
0
0
0
0
0
0
0
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% F
% Gly:
0
15
0
0
0
15
0
0
0
86
0
0
15
86
0
% G
% His:
0
0
0
0
0
0
0
15
15
0
0
0
0
0
0
% H
% Ile:
15
0
0
15
0
0
15
0
0
0
0
0
0
0
0
% I
% Lys:
15
0
15
0
0
0
15
15
0
0
15
0
0
0
29
% K
% Leu:
0
0
0
0
15
0
0
0
43
0
15
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
0
0
86
0
0
0
0
15
0
0
0
0
0
0
0
% P
% Gln:
0
58
0
0
0
0
0
0
0
0
15
0
15
0
15
% Q
% Arg:
15
0
0
0
15
0
0
0
0
0
58
0
72
0
29
% R
% Ser:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
15
% S
% Thr:
0
0
0
0
0
29
72
29
15
0
0
0
0
0
0
% T
% Val:
0
0
0
29
72
0
0
0
15
0
0
72
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
15
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _