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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHIPL2
All Species:
24.55
Human Site:
S312
Identified Species:
60
UniProt:
Q6UWX4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWX4
NP_079022.2
724
80779
S312
R
I
S
E
M
K
V
S
R
A
D
P
N
K
A
Chimpanzee
Pan troglodytes
XP_525070
724
80720
S312
R
I
S
E
M
K
V
S
R
A
D
P
N
K
A
Rhesus Macaque
Macaca mulatta
XP_001093950
700
78823
I318
A
I
G
P
H
D
H
I
L
R
V
V
E
Y
T
Dog
Lupus familis
XP_536153
696
77919
S306
R
I
S
E
M
K
V
S
R
A
D
P
N
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2G9
717
79980
S311
R
I
S
E
M
K
V
S
L
S
D
G
N
R
A
Rat
Rattus norvegicus
XP_229754
712
79186
S311
R
I
S
Q
M
K
V
S
L
S
D
P
N
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512074
768
85288
S311
R
I
S
E
M
K
A
S
R
A
D
A
N
K
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079267
995
110798
E316
R
I
S
E
F
Q
V
E
E
H
D
I
N
K
A
Zebra Danio
Brachydanio rerio
XP_688873
814
91909
S316
R
I
S
E
M
K
V
S
A
H
D
M
N
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794447
1074
120429
M292
R
I
S
E
F
Q
T
M
S
N
D
S
N
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.4
79.2
N.A.
83.1
82.1
N.A.
72
N.A.
48.5
57.3
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
99.7
44.2
86.3
N.A.
89.9
88.6
N.A.
80.4
N.A.
58.6
70.2
N.A.
N.A.
N.A.
N.A.
44.9
P-Site Identity:
100
100
6.6
93.3
N.A.
73.3
80
N.A.
86.6
N.A.
60
73.3
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
6.6
100
N.A.
86.6
93.3
N.A.
86.6
N.A.
66.6
73.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
10
40
0
10
0
0
80
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
90
0
0
0
0
% D
% Glu:
0
0
0
80
0
0
0
10
10
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
0
10
0
0
20
0
0
0
0
0
% H
% Ile:
0
100
0
0
0
0
0
10
0
0
0
10
0
10
0
% I
% Lys:
0
0
0
0
0
70
0
0
0
0
0
0
0
50
0
% K
% Leu:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% L
% Met:
0
0
0
0
70
0
0
10
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
90
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
40
0
0
0
% P
% Gln:
0
0
0
10
0
20
0
0
0
0
0
0
0
0
0
% Q
% Arg:
90
0
0
0
0
0
0
0
40
10
0
0
0
30
0
% R
% Ser:
0
0
90
0
0
0
0
70
10
20
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
70
0
0
0
10
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _