KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHIPL2
All Species:
31.21
Human Site:
S374
Identified Species:
76.3
UniProt:
Q6UWX4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWX4
NP_079022.2
724
80779
S374
F
G
N
A
Q
N
K
S
S
L
L
G
K
V
L
Chimpanzee
Pan troglodytes
XP_525070
724
80720
S374
F
G
N
A
Q
N
K
S
S
L
L
G
K
V
L
Rhesus Macaque
Macaca mulatta
XP_001093950
700
78823
L376
L
G
D
G
M
I
T
L
D
D
M
E
E
M
D
Dog
Lupus familis
XP_536153
696
77919
S368
F
G
N
A
Q
N
K
S
S
L
L
G
K
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2G9
717
79980
S373
F
G
N
A
Q
N
K
S
S
L
L
G
K
V
L
Rat
Rattus norvegicus
XP_229754
712
79186
S373
F
G
N
A
Q
N
K
S
S
L
L
G
K
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512074
768
85288
S373
F
G
N
A
Q
N
K
S
S
L
L
G
K
V
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079267
995
110798
S378
F
G
N
A
Q
N
K
S
V
L
L
G
K
V
L
Zebra Danio
Brachydanio rerio
XP_688873
814
91909
S378
F
G
N
A
Q
N
R
S
A
L
L
G
K
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794447
1074
120429
A354
Y
G
N
A
Q
N
L
A
E
L
L
G
S
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.4
79.2
N.A.
83.1
82.1
N.A.
72
N.A.
48.5
57.3
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
99.7
44.2
86.3
N.A.
89.9
88.6
N.A.
80.4
N.A.
58.6
70.2
N.A.
N.A.
N.A.
N.A.
44.9
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
N.A.
93.3
80
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
90
0
0
0
10
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
10
10
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
0
% E
% Phe:
80
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
10
0
0
0
0
0
0
0
90
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
70
0
0
0
0
0
80
0
0
% K
% Leu:
10
0
0
0
0
0
10
10
0
90
90
0
0
0
80
% L
% Met:
0
0
0
0
10
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
0
0
90
0
0
90
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
80
60
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
80
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _