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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHIPL2
All Species:
12.42
Human Site:
S620
Identified Species:
30.37
UniProt:
Q6UWX4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWX4
NP_079022.2
724
80779
S620
P
V
P
V
R
T
K
S
K
R
I
P
F
R
P
Chimpanzee
Pan troglodytes
XP_525070
724
80720
S620
P
V
P
V
R
T
K
S
K
R
I
P
F
R
P
Rhesus Macaque
Macaca mulatta
XP_001093950
700
78823
V598
P
E
E
C
R
A
T
V
Q
P
A
P
T
L
T
Dog
Lupus familis
XP_536153
696
77919
V592
H
G
S
I
Y
K
F
V
D
P
S
R
R
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2G9
717
79980
V614
C
K
Y
K
P
V
P
V
K
T
K
S
K
K
V
Rat
Rattus norvegicus
XP_229754
712
79186
P611
P
G
K
C
K
L
K
P
V
P
V
R
A
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512074
768
85288
S619
P
L
P
V
K
V
K
S
K
R
I
P
F
T
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079267
995
110798
S624
P
V
P
V
K
T
R
S
K
L
V
P
F
I
P
Zebra Danio
Brachydanio rerio
XP_688873
814
91909
G624
P
L
P
V
K
V
R
G
K
K
V
P
F
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794447
1074
120429
G923
I
R
D
V
D
V
H
G
P
T
T
P
F
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.4
79.2
N.A.
83.1
82.1
N.A.
72
N.A.
48.5
57.3
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
99.7
44.2
86.3
N.A.
89.9
88.6
N.A.
80.4
N.A.
58.6
70.2
N.A.
N.A.
N.A.
N.A.
44.9
P-Site Identity:
100
100
20
6.6
N.A.
6.6
13.3
N.A.
73.3
N.A.
66.6
46.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
26.6
13.3
N.A.
13.3
33.3
N.A.
86.6
N.A.
86.6
80
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
10
0
10
10
0
% A
% Cys:
10
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
60
0
0
% F
% Gly:
0
20
0
0
0
0
0
20
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
0
0
0
0
30
0
0
10
0
% I
% Lys:
0
10
10
10
40
10
40
0
60
10
10
0
10
20
0
% K
% Leu:
0
20
0
0
0
10
0
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
70
0
50
0
10
0
10
10
10
30
0
70
0
0
70
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
30
0
20
0
0
30
0
20
10
20
0
% R
% Ser:
0
0
10
0
0
0
0
40
0
0
10
10
0
0
10
% S
% Thr:
0
0
0
0
0
30
10
0
0
20
10
0
10
20
10
% T
% Val:
0
30
0
60
0
40
0
30
10
0
30
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _