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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHIPL2
All Species:
7.58
Human Site:
S661
Identified Species:
18.52
UniProt:
Q6UWX4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWX4
NP_079022.2
724
80779
S661
S
G
P
A
Q
G
L
S
E
K
G
S
S
K
K
Chimpanzee
Pan troglodytes
XP_525070
724
80720
S661
S
G
P
A
Q
G
L
S
E
K
G
S
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001093950
700
78823
C639
D
F
C
R
I
A
K
C
E
P
A
C
R
H
G
Dog
Lupus familis
XP_536153
696
77919
Q633
V
L
D
L
L
K
E
Q
S
E
K
A
A
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2G9
717
79980
D655
A
T
F
T
S
S
S
D
R
V
A
S
Q
K
G
Rat
Rattus norvegicus
XP_229754
712
79186
S652
P
S
T
S
T
L
A
S
S
S
D
R
A
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512074
768
85288
V660
S
S
V
P
T
R
H
V
H
S
A
R
K
G
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079267
995
110798
T665
F
P
T
K
V
P
P
T
P
T
K
F
P
T
K
Zebra Danio
Brachydanio rerio
XP_688873
814
91909
R665
P
G
T
R
Q
P
T
R
A
K
P
S
T
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794447
1074
120429
T964
A
K
F
V
I
T
G
T
V
R
K
A
Q
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.4
79.2
N.A.
83.1
82.1
N.A.
72
N.A.
48.5
57.3
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
99.7
44.2
86.3
N.A.
89.9
88.6
N.A.
80.4
N.A.
58.6
70.2
N.A.
N.A.
N.A.
N.A.
44.9
P-Site Identity:
100
100
6.6
6.6
N.A.
13.3
6.6
N.A.
6.6
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
6.6
33.3
N.A.
20
20
N.A.
6.6
N.A.
13.3
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
20
0
10
10
0
10
0
30
20
20
10
10
% A
% Cys:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
30
10
0
0
0
0
0
% E
% Phe:
10
10
20
0
0
0
0
0
0
0
0
10
0
0
10
% F
% Gly:
0
30
0
0
0
20
10
0
0
0
20
0
0
10
20
% G
% His:
0
0
0
0
0
0
10
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
0
10
10
0
0
30
30
0
10
30
40
% K
% Leu:
0
10
0
10
10
10
20
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
10
20
10
0
20
10
0
10
10
10
0
10
0
10
% P
% Gln:
0
0
0
0
30
0
0
10
0
0
0
0
20
0
0
% Q
% Arg:
0
0
0
20
0
10
0
10
10
10
0
20
10
20
0
% R
% Ser:
30
20
0
10
10
10
10
30
20
20
0
40
20
10
10
% S
% Thr:
0
10
30
10
20
10
10
20
0
10
0
0
10
10
0
% T
% Val:
10
0
10
10
10
0
0
10
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _