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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHIPL2
All Species:
10.3
Human Site:
S707
Identified Species:
25.19
UniProt:
Q6UWX4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWX4
NP_079022.2
724
80779
S707
R
K
S
L
K
S
H
S
G
R
M
R
P
S
A
Chimpanzee
Pan troglodytes
XP_525070
724
80720
S707
R
K
S
L
K
S
H
S
G
R
M
R
P
S
A
Rhesus Macaque
Macaca mulatta
XP_001093950
700
78823
D683
V
T
R
A
G
I
L
D
Q
I
I
D
M
T
S
Dog
Lupus familis
XP_536153
696
77919
T678
K
M
F
Q
R
P
G
T
K
K
R
A
R
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2G9
717
79980
N700
P
Q
G
K
R
K
P
N
L
D
S
H
G
V
G
Rat
Rattus norvegicus
XP_229754
712
79186
G695
M
W
S
P
G
P
Q
G
K
R
K
Q
S
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512074
768
85288
C742
R
K
A
R
D
A
V
C
L
Q
C
S
L
S
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079267
995
110798
T947
K
T
G
V
N
N
K
T
K
N
L
P
P
K
A
Zebra Danio
Brachydanio rerio
XP_688873
814
91909
T792
S
Q
P
E
G
T
V
T
K
K
T
Q
A
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794447
1074
120429
H1050
V
K
R
Y
H
W
H
H
S
F
M
I
P
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.4
79.2
N.A.
83.1
82.1
N.A.
72
N.A.
48.5
57.3
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
99.7
44.2
86.3
N.A.
89.9
88.6
N.A.
80.4
N.A.
58.6
70.2
N.A.
N.A.
N.A.
N.A.
44.9
P-Site Identity:
100
100
0
0
N.A.
0
20
N.A.
20
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
20
33.3
N.A.
20
26.6
N.A.
40
N.A.
46.6
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
10
0
0
0
0
0
10
10
10
40
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
10
0
10
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
20
0
30
0
10
10
20
0
0
0
10
0
10
% G
% His:
0
0
0
0
10
0
30
10
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
10
10
10
0
0
0
% I
% Lys:
20
40
0
10
20
10
10
0
40
20
10
0
0
10
0
% K
% Leu:
0
0
0
20
0
0
10
0
20
0
10
0
10
0
10
% L
% Met:
10
10
0
0
0
0
0
0
0
0
30
0
10
0
0
% M
% Asn:
0
0
0
0
10
10
0
10
0
10
0
0
0
0
0
% N
% Pro:
10
0
10
10
0
20
10
0
0
0
0
10
40
0
0
% P
% Gln:
0
20
0
10
0
0
10
0
10
10
0
20
0
10
10
% Q
% Arg:
30
0
20
10
20
0
0
0
0
30
10
20
10
10
10
% R
% Ser:
10
0
30
0
0
20
0
20
10
0
10
10
10
40
20
% S
% Thr:
0
20
0
0
0
10
0
30
0
0
10
0
0
10
0
% T
% Val:
20
0
0
10
0
0
20
0
0
0
0
0
0
10
0
% V
% Trp:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _