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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHIPL2
All Species:
33.94
Human Site:
T433
Identified Species:
82.96
UniProt:
Q6UWX4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWX4
NP_079022.2
724
80779
T433
V
D
R
G
D
P
I
T
R
Q
G
R
G
R
I
Chimpanzee
Pan troglodytes
XP_525070
724
80720
T433
V
D
R
G
D
P
V
T
R
Q
G
R
G
R
I
Rhesus Macaque
Macaca mulatta
XP_001093950
700
78823
G433
A
H
G
L
H
D
P
G
R
C
A
V
D
R
H
Dog
Lupus familis
XP_536153
696
77919
T427
V
D
R
G
D
P
V
T
R
Q
G
R
G
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2G9
717
79980
T432
V
D
R
G
D
P
V
T
H
R
G
R
G
R
I
Rat
Rattus norvegicus
XP_229754
712
79186
T432
V
D
R
G
D
P
V
T
R
Q
G
R
G
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512074
768
85288
T432
V
D
R
G
D
P
A
T
H
R
G
R
G
R
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079267
995
110798
T437
V
D
Q
G
D
P
V
T
G
R
G
K
G
R
I
Zebra Danio
Brachydanio rerio
XP_688873
814
91909
T437
V
D
R
G
D
P
L
T
R
Y
G
R
G
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794447
1074
120429
T414
I
D
Q
G
D
R
Q
T
G
E
G
R
G
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.4
79.2
N.A.
83.1
82.1
N.A.
72
N.A.
48.5
57.3
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
99.7
44.2
86.3
N.A.
89.9
88.6
N.A.
80.4
N.A.
58.6
70.2
N.A.
N.A.
N.A.
N.A.
44.9
P-Site Identity:
100
93.3
13.3
86.6
N.A.
80
93.3
N.A.
80
N.A.
66.6
86.6
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
100
N.A.
86.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
90
0
0
90
10
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
90
0
0
0
10
20
0
90
0
90
0
0
% G
% His:
0
10
0
0
10
0
0
0
20
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
80
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
80
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
20
0
0
0
10
0
0
40
0
0
0
0
0
% Q
% Arg:
0
0
70
0
0
10
0
0
60
30
0
80
0
100
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% T
% Val:
80
0
0
0
0
0
50
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _