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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHIPL2
All Species:
13.33
Human Site:
Y584
Identified Species:
32.59
UniProt:
Q6UWX4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWX4
NP_079022.2
724
80779
Y584
L
Y
F
L
A
T
S
Y
P
S
A
Y
A
P
R
Chimpanzee
Pan troglodytes
XP_525070
724
80720
Y584
L
Y
F
L
A
T
S
Y
P
S
A
Y
A
P
H
Rhesus Macaque
Macaca mulatta
XP_001093950
700
78823
V562
G
E
D
E
L
G
E
V
Y
I
L
S
S
S
K
Dog
Lupus familis
XP_536153
696
77919
Y556
F
P
G
L
I
S
T
Y
S
K
Y
I
I
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2G9
717
79980
L578
E
A
G
E
L
Y
F
L
A
T
S
Y
P
S
A
Rat
Rattus norvegicus
XP_229754
712
79186
L575
A
E
D
E
A
G
E
L
Y
F
L
A
T
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512074
768
85288
Y583
L
Y
F
L
S
T
S
Y
P
S
A
Y
T
P
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079267
995
110798
Q588
L
L
F
L
S
T
S
Q
A
S
A
Y
S
P
Q
Zebra Danio
Brachydanio rerio
XP_688873
814
91909
Y588
L
Y
F
L
A
T
S
Y
P
S
A
M
S
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794447
1074
120429
E563
M
Y
L
L
S
T
S
E
A
K
T
T
V
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.4
79.2
N.A.
83.1
82.1
N.A.
72
N.A.
48.5
57.3
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
99.7
44.2
86.3
N.A.
89.9
88.6
N.A.
80.4
N.A.
58.6
70.2
N.A.
N.A.
N.A.
N.A.
44.9
P-Site Identity:
100
93.3
0
13.3
N.A.
6.6
6.6
N.A.
80
N.A.
60
80
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
93.3
13.3
26.6
N.A.
20
6.6
N.A.
86.6
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
40
0
0
0
30
0
50
10
20
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
20
0
30
0
0
20
10
0
0
0
0
0
0
0
% E
% Phe:
10
0
50
0
0
0
10
0
0
10
0
0
0
0
20
% F
% Gly:
10
0
20
0
0
20
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
0
0
0
0
10
0
0
0
0
10
0
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
10
% K
% Leu:
50
10
10
70
20
0
0
20
0
0
20
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
40
0
0
0
10
60
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
20
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
30
10
60
0
10
50
10
10
30
40
0
% S
% Thr:
0
0
0
0
0
60
10
0
0
10
10
10
20
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
0
0
10
0
50
20
0
10
50
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _