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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM175A
All Species:
19.7
Human Site:
S126
Identified Species:
43.33
UniProt:
Q6UWZ7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWZ7
NP_620775.2
409
46663
S126
K
N
L
Q
E
H
F
S
N
Q
D
L
V
F
L
Chimpanzee
Pan troglodytes
XP_001135565
409
46616
S126
K
N
L
Q
E
H
F
S
N
Q
D
L
V
F
L
Rhesus Macaque
Macaca mulatta
XP_001116239
216
24956
Dog
Lupus familis
XP_535636
418
47420
S126
K
N
L
Q
K
H
L
S
S
Q
E
L
V
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPZ8
407
46021
S126
R
N
L
Q
T
H
L
S
S
P
E
L
V
F
L
Rat
Rattus norvegicus
Q5I0F1
405
45671
S126
R
N
L
Q
T
H
L
S
S
P
E
L
V
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520956
160
18426
Chicken
Gallus gallus
Q5ZHS0
405
46025
S126
K
N
L
Q
S
H
L
S
N
Q
G
L
V
F
L
Frog
Xenopus laevis
Q6GR31
408
45804
H126
L
H
K
N
L
Q
E
H
F
S
N
S
G
L
V
Zebra Danio
Brachydanio rerio
Q1LVP6
391
44617
L126
H
R
N
M
R
K
I
L
S
N
Q
E
L
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395910
456
51364
C126
K
E
F
A
S
Y
F
C
N
D
N
G
S
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
50.6
83.9
N.A.
72.3
71.8
N.A.
31
62.3
53.2
39.6
N.A.
N.A.
22.8
N.A.
N.A.
Protein Similarity:
100
100
51.5
91.8
N.A.
83.1
81.4
N.A.
34.9
78.9
72.3
61.3
N.A.
N.A.
45.3
N.A.
N.A.
P-Site Identity:
100
100
0
73.3
N.A.
60
60
N.A.
0
80
0
0
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
100
0
93.3
N.A.
80
80
N.A.
0
80
20
13.3
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
19
0
0
0
0
% D
% Glu:
0
10
0
0
19
0
10
0
0
0
28
10
0
0
0
% E
% Phe:
0
0
10
0
0
0
28
0
10
0
0
0
0
55
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
10
10
0
0
% G
% His:
10
10
0
0
0
55
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
46
0
10
0
10
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
0
55
0
10
0
37
10
0
0
0
55
10
10
55
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
55
10
10
0
0
0
0
37
10
19
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% P
% Gln:
0
0
0
55
0
10
0
0
0
37
10
0
0
0
0
% Q
% Arg:
19
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
19
0
0
55
37
10
0
10
10
0
0
% S
% Thr:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
55
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _