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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM175A All Species: 13.33
Human Site: S387 Identified Species: 29.33
UniProt: Q6UWZ7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UWZ7 NP_620775.2 409 46663 S387 D K A S K M S S P E T D E E I
Chimpanzee Pan troglodytes XP_001135565 409 46616 S387 D K A S K M S S P E T D E E I
Rhesus Macaque Macaca mulatta XP_001116239 216 24956 P195 K A S K M S S P E T D E E I E
Dog Lupus familis XP_535636 418 47420 S396 E K A S T V S S P E T D E D I
Cat Felis silvestris
Mouse Mus musculus Q8BPZ8 407 46021 L386 D K A S S S S L D I D I E M G
Rat Rattus norvegicus Q5I0F1 405 45671 S383 Q D K A S S S S L D I D T E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520956 160 18426 D139 R S E F F N E D G S L K E V H
Chicken Gallus gallus Q5ZHS0 405 46025 A383 T K L A L S S A E T D E E A L
Frog Xenopus laevis Q6GR31 408 45804 S384 S E K L L C T S G T E T D G D
Zebra Danio Brachydanio rerio Q1LVP6 391 44617 E367 R K T R E V S E S A S E S G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395910 456 51364 T431 E T N S V Q N T S L Q T Y S Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 50.6 83.9 N.A. 72.3 71.8 N.A. 31 62.3 53.2 39.6 N.A. N.A. 22.8 N.A. N.A.
Protein Similarity: 100 100 51.5 91.8 N.A. 83.1 81.4 N.A. 34.9 78.9 72.3 61.3 N.A. N.A. 45.3 N.A. N.A.
P-Site Identity: 100 100 13.3 73.3 N.A. 40 26.6 N.A. 6.6 20 6.6 13.3 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 26.6 93.3 N.A. 40 46.6 N.A. 6.6 46.6 26.6 40 N.A. N.A. 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 37 19 0 0 0 10 0 10 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 28 10 0 0 0 0 0 10 10 10 28 37 10 10 10 % D
% Glu: 19 10 10 0 10 0 10 10 19 28 10 28 64 28 10 % E
% Phe: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 19 0 0 0 0 19 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 10 10 0 10 28 % I
% Lys: 10 55 19 10 19 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 10 10 19 0 0 10 10 10 10 0 0 0 10 % L
% Met: 0 0 0 0 10 19 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 10 0 0 10 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 28 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 10 0 0 0 0 10 0 0 0 10 % Q
% Arg: 19 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 10 46 19 37 73 46 19 10 10 0 10 10 10 % S
% Thr: 10 10 10 0 10 0 10 10 0 28 28 19 10 0 0 % T
% Val: 0 0 0 0 10 19 0 0 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _