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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS13
All Species:
11.82
Human Site:
S335
Identified Species:
43.33
UniProt:
Q6UX07
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UX07
NP_653284.2
377
40849
S335
E
D
S
E
A
P
S
S
L
S
T
P
H
P
E
Chimpanzee
Pan troglodytes
XP_001136514
322
34982
S280
E
D
S
E
A
P
S
S
L
S
T
P
H
P
E
Rhesus Macaque
Macaca mulatta
XP_001109844
377
40807
S335
E
D
S
G
A
P
S
S
L
S
T
T
H
P
E
Dog
Lupus familis
XP_548293
377
40826
S335
E
D
P
R
T
P
S
S
P
S
S
P
H
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5SS80
376
40726
A333
P
E
P
E
D
P
R
A
P
S
S
Q
S
A
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506445
243
26521
V202
S
E
L
Y
L
R
H
V
P
G
W
L
R
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793866
335
37015
L294
C
A
V
S
D
D
I
L
D
Q
S
G
E
F
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.9
97.3
88.5
N.A.
83.2
N.A.
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
82.7
98.4
93
N.A.
90.7
N.A.
N.A.
54.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
57.2
P-Site Identity:
100
100
86.6
66.6
N.A.
20
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
73.3
N.A.
40
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
43
0
0
15
0
0
0
0
0
15
0
% A
% Cys:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
58
0
0
29
15
0
0
15
0
0
0
0
0
0
% D
% Glu:
58
29
0
43
0
0
0
0
0
0
0
0
15
0
58
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
15
% F
% Gly:
0
0
0
15
0
0
0
0
0
15
0
15
0
0
0
% G
% His:
0
0
0
0
0
0
15
0
0
0
0
0
58
0
0
% H
% Ile:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
0
15
0
0
15
43
0
0
15
0
15
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
0
29
0
0
72
0
0
43
0
0
43
0
58
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
15
0
15
0
0
0
% Q
% Arg:
0
0
0
15
0
15
15
0
0
0
0
0
15
0
0
% R
% Ser:
15
0
43
15
0
0
58
58
0
72
43
0
15
0
0
% S
% Thr:
0
0
0
0
15
0
0
0
0
0
43
15
0
0
0
% T
% Val:
0
0
15
0
0
0
0
15
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _