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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAYN
All Species:
21.82
Human Site:
T276
Identified Species:
60
UniProt:
Q6UX15
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UX15
NP_849156.1
382
43108
T276
P
S
T
K
K
Q
H
T
I
W
P
S
P
H
Q
Chimpanzee
Pan troglodytes
XP_508749
382
43098
T276
P
S
T
K
K
Q
H
T
I
W
P
S
P
H
Q
Rhesus Macaque
Macaca mulatta
XP_001105695
382
43063
T276
P
S
T
K
K
Q
H
T
I
W
P
S
P
H
Q
Dog
Lupus familis
XP_546529
503
54611
T397
P
S
T
K
E
Q
H
T
I
W
P
S
P
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C351
381
43181
T276
P
S
T
K
E
Q
H
T
I
W
P
T
P
R
Q
Rat
Rattus norvegicus
XP_576410
376
42696
T271
P
P
T
K
E
Q
H
T
I
W
P
T
P
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510411
255
28425
D150
P
Y
L
Y
Q
W
N
D
D
R
C
N
M
K
H
Chicken
Gallus gallus
XP_001231435
275
30026
D170
P
Y
L
Y
Q
W
N
D
D
R
C
N
M
K
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693396
388
44187
P281
K
E
Q
T
E
T
P
P
K
D
P
G
Y
W
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
64.4
N.A.
83.7
79
N.A.
34.5
39
N.A.
50
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.1
69.3
N.A.
89.7
84.5
N.A.
47.3
50
N.A.
63.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
26.6
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
23
23
12
0
0
0
0
0
% D
% Glu:
0
12
0
0
45
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
67
0
0
0
0
0
0
45
23
% H
% Ile:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% I
% Lys:
12
0
0
67
34
0
0
0
12
0
0
0
0
23
0
% K
% Leu:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% M
% Asn:
0
0
0
0
0
0
23
0
0
0
0
23
0
0
0
% N
% Pro:
89
12
0
0
0
0
12
12
0
0
78
0
67
0
0
% P
% Gln:
0
0
12
0
23
67
0
0
0
0
0
0
0
0
67
% Q
% Arg:
0
0
0
0
0
0
0
0
0
23
0
0
0
23
0
% R
% Ser:
0
56
0
0
0
0
0
0
0
0
0
45
0
0
0
% S
% Thr:
0
0
67
12
0
12
0
67
0
0
0
23
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
23
0
0
0
67
0
0
0
12
0
% W
% Tyr:
0
23
0
23
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _