KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRAM2
All Species:
19.7
Human Site:
T249
Identified Species:
48.15
UniProt:
Q6UX65
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UX65
NP_848549.3
266
29766
T249
H
G
L
T
L
Y
D
T
A
P
C
P
I
N
N
Chimpanzee
Pan troglodytes
XP_001161746
270
30195
Q249
S
D
F
L
L
L
V
Q
E
G
G
L
R
E
L
Rhesus Macaque
Macaca mulatta
XP_001104325
266
29738
T249
H
G
L
T
L
Y
D
T
A
P
C
P
I
N
S
Dog
Lupus familis
XP_537031
266
29852
T249
H
G
L
T
L
Y
D
T
A
P
C
P
V
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR48
267
30209
T249
H
G
L
T
L
Y
D
T
V
P
C
P
V
N
N
Rat
Rattus norvegicus
Q5BK09
267
30154
T249
H
G
L
T
L
Y
D
T
V
P
C
P
V
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512378
363
40118
A346
E
G
L
T
L
Y
D
A
A
P
C
H
I
N
S
Chicken
Gallus gallus
XP_419233
266
29997
T249
H
G
Q
T
L
Y
N
T
P
Q
S
F
A
T
D
Frog
Xenopus laevis
Q6NRS6
239
26604
D223
Y
F
L
T
F
I
R
D
F
Q
G
V
S
I
Q
Zebra Danio
Brachydanio rerio
Q32PK2
232
25997
L216
L
T
V
Q
K
E
G
L
K
V
A
N
N
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
97.7
91.7
N.A.
85.7
85.3
N.A.
51.7
62
35.7
25.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.3
99.2
95.8
N.A.
92.8
92.1
N.A.
61.4
80.8
58.6
43.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
93.3
N.A.
86.6
80
N.A.
73.3
40
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
93.3
86.6
N.A.
80
53.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
40
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
60
10
0
0
0
0
0
10
10
% D
% Glu:
10
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% E
% Phe:
0
10
10
0
10
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
0
70
0
0
0
0
10
0
0
10
20
0
0
0
0
% G
% His:
60
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
30
10
0
% I
% Lys:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
0
70
10
80
10
0
10
0
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
10
10
50
50
% N
% Pro:
0
0
0
0
0
0
0
0
10
60
0
50
0
0
0
% P
% Gln:
0
0
10
10
0
0
0
10
0
20
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
10
0
10
0
20
% S
% Thr:
0
10
0
80
0
0
0
60
0
0
0
0
0
20
0
% T
% Val:
0
0
10
0
0
0
10
0
20
10
0
10
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _