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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC24 All Species: 30.91
Human Site: S107 Identified Species: 56.67
UniProt: Q6UX98 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UX98 NP_997223.1 284 30176 S107 Q S Q V P P R S G H C S A C R
Chimpanzee Pan troglodytes XP_001150922 259 27480 R87 R G V M L A G R G L G Q G W A
Rhesus Macaque Macaca mulatta XP_001109934 284 30169 S107 Q S Q V P P R S G H C S A C R
Dog Lupus familis XP_540829 284 30259 S107 Q S Q V P P R S G H C S A C R
Cat Felis silvestris
Mouse Mus musculus Q6IR37 284 30412 S107 Q S Q V P P R S G H C S A C R
Rat Rattus norvegicus Q2TGI5 284 30678 S107 Q S Q V P P R S G H C S A C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q5FWL7 338 39422 C142 Q M V K P D R C H H C S V C G
Zebra Danio Brachydanio rerio NP_001002324 295 33688 C115 E T H T P P R C S H C Y D C N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611671 278 32149 S104 Q K L A P P R S W H C K A C K
Honey Bee Apis mellifera XP_001120472 285 33881 S106 E T L A P P R S W H C S I C N
Nematode Worm Caenorhab. elegans Q8I0G4 403 46434 S145 C C I K P D R S H H C S M C E
Sea Urchin Strong. purpuratus XP_001190341 283 32925 S105 T L N T P P R S S H C F V C N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q500Z2 254 28625 T88 F A Y K P L R T H H C R V C R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 98.9 95.4 N.A. 87.6 88 N.A. N.A. N.A. 23 43 N.A. 27.4 30.1 20.6 31.6
Protein Similarity: 100 90.4 99.6 96.4 N.A. 92.2 92.6 N.A. N.A. N.A. 35.2 55.5 N.A. 43.6 46.3 33.5 47.8
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. N.A. 46.6 40 N.A. 60 53.3 46.6 46.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. N.A. N.A. 46.6 53.3 N.A. 66.6 66.6 46.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 16 0 8 0 0 0 0 0 0 47 0 8 % A
% Cys: 8 8 0 0 0 0 0 16 0 0 93 0 0 93 0 % C
% Asp: 0 0 0 0 0 16 0 0 0 0 0 0 8 0 0 % D
% Glu: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 0 0 8 0 47 0 8 0 8 0 8 % G
% His: 0 0 8 0 0 0 0 0 24 93 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 8 0 24 0 0 0 0 0 0 0 8 0 0 8 % K
% Leu: 0 8 16 0 8 8 0 0 0 8 0 0 0 0 0 % L
% Met: 0 8 0 8 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 24 % N
% Pro: 0 0 0 0 93 70 0 0 0 0 0 0 0 0 0 % P
% Gln: 54 0 39 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 8 0 0 0 0 0 93 8 0 0 0 8 0 0 47 % R
% Ser: 0 39 0 0 0 0 0 70 16 0 0 62 0 0 0 % S
% Thr: 8 16 0 16 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 0 16 39 0 0 0 0 0 0 0 0 24 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 16 0 0 0 0 8 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _