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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC24
All Species:
24.85
Human Site:
T275
Identified Species:
45.56
UniProt:
Q6UX98
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UX98
NP_997223.1
284
30176
T275
G
D
G
I
T
F
Q
T
T
A
D
V
G
H
T
Chimpanzee
Pan troglodytes
XP_001150922
259
27480
T250
G
D
G
I
T
F
Q
T
T
A
D
V
G
H
T
Rhesus Macaque
Macaca mulatta
XP_001109934
284
30169
T275
G
D
G
I
T
F
Q
T
T
A
D
V
G
H
T
Dog
Lupus familis
XP_540829
284
30259
T275
G
D
G
I
T
F
Q
T
A
A
D
V
G
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6IR37
284
30412
T275
G
D
G
I
S
F
Q
T
P
G
D
V
G
L
V
Rat
Rattus norvegicus
Q2TGI5
284
30678
T275
G
D
G
I
T
F
Q
T
P
T
D
V
G
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5FWL7
338
39422
E322
E
D
D
L
T
D
E
E
S
Q
A
Y
C
E
T
Zebra Danio
Brachydanio rerio
NP_001002324
295
33688
V283
G
D
G
I
N
F
K
V
T
A
S
L
E
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611671
278
32149
Y268
S
D
L
P
E
D
G
Y
H
W
N
V
P
T
N
Honey Bee
Apis mellifera
XP_001120472
285
33881
T273
H
N
G
V
I
W
D
T
S
N
S
W
F
Y
T
Nematode Worm
Caenorhab. elegans
Q8I0G4
403
46434
T392
R
S
Q
V
S
T
A
T
T
A
S
P
S
H
D
Sea Urchin
Strong. purpuratus
XP_001190341
283
32925
K272
G
D
G
I
H
F
V
K
R
D
K
S
L
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q500Z2
254
28625
R240
W
L
C
P
T
F
T
R
N
P
E
D
G
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
98.9
95.4
N.A.
87.6
88
N.A.
N.A.
N.A.
23
43
N.A.
27.4
30.1
20.6
31.6
Protein Similarity:
100
90.4
99.6
96.4
N.A.
92.2
92.6
N.A.
N.A.
N.A.
35.2
55.5
N.A.
43.6
46.3
33.5
47.8
P-Site Identity:
100
100
100
86.6
N.A.
66.6
73.3
N.A.
N.A.
N.A.
20
46.6
N.A.
13.3
20
26.6
33.3
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
N.A.
N.A.
40
60
N.A.
20
53.3
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
47
8
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
77
8
0
0
16
8
0
0
8
47
8
0
0
8
% D
% Glu:
8
0
0
0
8
0
8
8
0
0
8
0
8
16
0
% E
% Phe:
0
0
0
0
0
70
0
0
0
0
0
0
8
0
0
% F
% Gly:
62
0
70
0
0
0
8
0
0
8
0
0
54
0
0
% G
% His:
8
0
0
0
8
0
0
0
8
0
0
0
0
31
0
% H
% Ile:
0
0
0
62
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
8
8
0
0
8
0
0
0
8
% K
% Leu:
0
8
8
8
0
0
0
0
0
0
0
8
8
24
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
8
8
8
0
0
0
16
% N
% Pro:
0
0
0
16
0
0
0
0
16
8
0
8
8
8
0
% P
% Gln:
0
0
8
0
0
0
47
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
16
0
0
0
16
0
24
8
8
0
8
% S
% Thr:
0
0
0
0
54
8
8
62
39
8
0
0
0
8
47
% T
% Val:
0
0
0
16
0
0
8
8
0
0
0
54
0
0
16
% V
% Trp:
8
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _