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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD7
All Species:
1.21
Human Site:
S498
Identified Species:
2.96
UniProt:
Q6UXD7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXD7
NP_115595.2
560
58427
S498
E
C
T
A
R
G
A
S
L
E
D
P
R
G
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086197
249
26101
K188
L
S
P
A
L
V
K
K
G
E
D
I
L
L
M
Dog
Lupus familis
XP_545988
457
48770
Q396
E
P
S
T
S
T
C
Q
D
G
Q
G
P
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CE47
516
54628
E455
P
Y
R
R
L
E
A
E
S
G
G
S
S
S
P
Rat
Rattus norvegicus
NP_001100716
516
54545
E455
P
Y
R
R
L
E
A
E
S
G
G
S
S
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232999
444
48179
S383
R
V
S
K
D
P
S
S
T
C
A
L
D
Q
D
Frog
Xenopus laevis
NP_001091154
484
52538
E423
T
R
P
F
A
P
S
E
P
S
P
C
G
I
H
Zebra Danio
Brachydanio rerio
Q503P5
474
50172
S413
A
L
A
T
P
T
H
S
P
T
S
V
C
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11073
507
55131
I446
D
N
T
M
S
I
M
I
F
S
L
L
A
T
L
Sea Urchin
Strong. purpuratus
XP_790583
543
58583
M482
S
A
V
T
T
S
M
M
S
T
M
P
D
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
38.3
56
N.A.
65
65.7
N.A.
N.A.
44.2
44.4
43.5
N.A.
N.A.
N.A.
30.3
36.2
Protein Similarity:
100
N.A.
41.2
65.5
N.A.
74.8
75.3
N.A.
N.A.
56.6
59.6
58.3
N.A.
N.A.
N.A.
49.2
52.1
P-Site Identity:
100
N.A.
20
6.6
N.A.
13.3
13.3
N.A.
N.A.
6.6
0
6.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
20
13.3
N.A.
13.3
13.3
N.A.
N.A.
20
6.6
6.6
N.A.
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
20
10
0
30
0
0
0
10
0
10
10
10
% A
% Cys:
0
10
0
0
0
0
10
0
0
10
0
10
10
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
10
0
20
0
20
10
20
% D
% Glu:
20
0
0
0
0
20
0
30
0
20
0
0
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
30
20
10
10
10
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
10
0
10
0
0
0
10
0
10
0
% I
% Lys:
0
0
0
10
0
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
30
0
0
0
10
0
10
20
10
20
10
% L
% Met:
0
0
0
10
0
0
20
10
0
0
10
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
10
20
0
10
20
0
0
20
0
10
20
10
0
30
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% Q
% Arg:
10
10
20
20
10
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
10
20
0
20
10
20
30
30
20
10
20
20
20
0
% S
% Thr:
10
0
20
30
10
20
0
0
10
20
0
0
0
10
0
% T
% Val:
0
10
10
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _