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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD7
All Species:
2.42
Human Site:
T489
Identified Species:
5.93
UniProt:
Q6UXD7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXD7
NP_115595.2
560
58427
T489
V
L
G
P
S
T
A
T
P
E
C
T
A
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086197
249
26101
N179
S
L
G
V
L
V
A
N
M
L
S
P
A
L
V
Dog
Lupus familis
XP_545988
457
48770
R387
L
T
A
L
S
V
R
R
A
E
P
S
T
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CE47
516
54628
N446
C
V
L
V
I
F
F
N
T
P
Y
R
R
L
E
Rat
Rattus norvegicus
NP_001100716
516
54545
N446
C
V
L
V
I
F
F
N
T
P
Y
R
R
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232999
444
48179
T374
M
V
L
L
Q
A
L
T
V
R
V
S
K
D
P
Frog
Xenopus laevis
NP_001091154
484
52538
K414
I
Y
M
I
L
F
Q
K
L
T
R
P
F
A
P
Zebra Danio
Brachydanio rerio
Q503P5
474
50172
L404
A
A
L
Y
L
L
L
L
Q
A
L
A
T
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11073
507
55131
P437
P
D
D
T
I
N
T
P
K
D
N
T
M
S
I
Sea Urchin
Strong. purpuratus
XP_790583
543
58583
S473
N
V
T
S
T
L
S
S
D
S
A
V
T
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
38.3
56
N.A.
65
65.7
N.A.
N.A.
44.2
44.4
43.5
N.A.
N.A.
N.A.
30.3
36.2
Protein Similarity:
100
N.A.
41.2
65.5
N.A.
74.8
75.3
N.A.
N.A.
56.6
59.6
58.3
N.A.
N.A.
N.A.
49.2
52.1
P-Site Identity:
100
N.A.
26.6
13.3
N.A.
0
0
N.A.
N.A.
6.6
0
0
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
N.A.
26.6
26.6
N.A.
6.6
6.6
N.A.
N.A.
26.6
6.6
0
N.A.
N.A.
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
10
20
0
10
10
10
10
20
10
0
% A
% Cys:
20
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
10
10
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
20
% E
% Phe:
0
0
0
0
0
30
20
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
30
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
0
% K
% Leu:
10
20
40
20
30
20
20
10
10
10
10
0
0
30
0
% L
% Met:
10
0
10
0
0
0
0
0
10
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
0
10
0
30
0
0
10
0
0
0
0
% N
% Pro:
10
0
0
10
0
0
0
10
10
20
10
20
0
10
20
% P
% Gln:
0
0
0
0
10
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
10
10
20
20
10
0
% R
% Ser:
10
0
0
10
20
0
10
10
0
10
10
20
0
20
10
% S
% Thr:
0
10
10
10
10
10
10
20
20
10
0
20
30
10
20
% T
% Val:
10
40
0
30
0
20
0
0
10
0
10
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
0
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _