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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MFSD7 All Species: 2.42
Human Site: Y446 Identified Species: 5.93
UniProt: Q6UXD7 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UXD7 NP_115595.2 560 58427 Y446 A V F F H T P Y R R L Q A E S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086197 249 26101 A139 G Q S L C A L A Q S L V I F S
Dog Lupus familis XP_545988 457 48770 E347 S V V P I A M E L A V E C S F
Cat Felis silvestris
Mouse Mus musculus Q8CE47 516 54628 R406 L T A L T V R R T G P S F S T
Rat Rattus norvegicus NP_001100716 516 54545 R406 L T A V T V R R T G P S F S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232999 444 48179 P334 A V K G A L L P C T E E A G L
Frog Xenopus laevis NP_001091154 484 52538 S374 G L F G F A I S P I A M E L A
Zebra Danio Brachydanio rerio Q503P5 474 50172 S364 C F G L F G Y S V Y P V G M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q11073 507 55131 S397 S T G L I V L S G Q I Q S V I
Sea Urchin Strong. purpuratus XP_790583 543 58583 L433 M L Q M S G Q L Q G I I L I I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 38.3 56 N.A. 65 65.7 N.A. N.A. 44.2 44.4 43.5 N.A. N.A. N.A. 30.3 36.2
Protein Similarity: 100 N.A. 41.2 65.5 N.A. 74.8 75.3 N.A. N.A. 56.6 59.6 58.3 N.A. N.A. N.A. 49.2 52.1
P-Site Identity: 100 N.A. 13.3 6.6 N.A. 0 0 N.A. N.A. 20 6.6 0 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 N.A. 20 26.6 N.A. 6.6 6.6 N.A. N.A. 26.6 20 0 N.A. N.A. N.A. 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 20 0 10 30 0 10 0 10 10 0 20 0 10 % A
% Cys: 10 0 0 0 10 0 0 0 10 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 10 20 10 10 10 % E
% Phe: 0 10 20 10 20 0 0 0 0 0 0 0 20 10 10 % F
% Gly: 20 0 20 20 0 20 0 0 10 30 0 0 10 10 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 20 0 10 0 0 10 20 10 10 10 20 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 20 20 0 40 0 10 30 10 10 0 20 0 10 10 10 % L
% Met: 10 0 0 10 0 0 10 0 0 0 0 10 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 10 10 10 0 30 0 0 0 0 % P
% Gln: 0 10 10 0 0 0 10 0 20 10 0 20 0 0 0 % Q
% Arg: 0 0 0 0 0 0 20 20 10 10 0 0 0 0 0 % R
% Ser: 20 0 10 0 10 0 0 30 0 10 0 20 10 30 20 % S
% Thr: 0 30 0 0 20 10 0 0 20 10 0 0 0 0 20 % T
% Val: 0 30 10 10 0 30 0 0 10 0 10 20 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _