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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM108
All Species:
14.85
Human Site:
Y549
Identified Species:
40.83
UniProt:
Q6UXF1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXF1
NP_001129941.1
575
59948
Y549
R
S
P
A
N
G
D
Y
R
D
T
G
M
V
L
Chimpanzee
Pan troglodytes
XP_516759
564
59326
R539
S
P
A
N
G
D
Y
R
D
T
G
M
V
L
V
Rhesus Macaque
Macaca mulatta
XP_001115415
575
59848
Y549
R
S
P
A
N
G
D
Y
R
D
T
G
M
V
L
Dog
Lupus familis
XP_853456
588
61845
Y562
R
S
P
A
N
G
D
Y
R
D
T
G
M
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHE4
574
59623
Y548
R
S
P
A
N
G
D
Y
R
D
T
G
M
V
L
Rat
Rattus norvegicus
P13838
378
38407
G353
G
E
E
E
P
L
V
G
S
E
D
E
A
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513921
398
43412
R373
S
P
A
N
G
D
Y
R
D
S
G
M
V
L
V
Chicken
Gallus gallus
XP_418792
467
49860
R442
S
P
A
N
G
D
Y
R
D
S
G
M
V
L
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691545
493
53261
S468
L
P
P
N
G
D
Y
S
D
S
G
V
V
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.8
94.6
79
N.A.
76.8
21.7
N.A.
39.4
44.3
N.A.
33
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.7
96
83.3
N.A.
80.5
33
N.A.
45.7
54.2
N.A.
46.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
20
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
45
0
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
45
45
0
45
45
12
0
0
0
0
% D
% Glu:
0
12
12
12
0
0
0
0
0
12
0
12
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
45
45
0
12
0
0
45
45
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
0
12
0
0
0
0
0
0
0
45
45
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
34
45
0
0
% M
% Asn:
0
0
0
45
45
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
45
56
0
12
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
45
0
0
0
0
0
0
34
45
0
0
0
0
0
0
% R
% Ser:
34
45
0
0
0
0
0
12
12
34
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
45
0
0
0
0
% T
% Val:
0
0
0
0
0
0
12
0
0
0
0
12
45
56
45
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
45
45
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _