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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPNT All Species: 4.55
Human Site: T376 Identified Species: 11.11
UniProt: Q6UXI9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UXI9 NP_001028219.1 565 61893 T376 T V D N R V Q T D P Q K P R G
Chimpanzee Pan troglodytes XP_517382 546 59733 V376 G I T V D N R V Q T D P Q K P
Rhesus Macaque Macaca mulatta Q2Q426 822 90769 N371 V Q K Q V D R N V T L R Q N Q
Dog Lupus familis XP_545014 566 62118 K376 R I Q T D P Q K P R G D V F I
Cat Felis silvestris
Mouse Mus musculus Q91V88 561 61472 T376 T V D N R I Q T D P Q K P R G
Rat Rattus norvegicus Q9WVH8 448 50142 N296 I N E C E H R N H T C T P L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511247 620 68609 E420 V E T T S P G E I T V D N R I
Chicken Gallus gallus XP_420498 531 57845 I366 T D D N R I Q I D P Q K P R G
Frog Xenopus laevis Q8AVH7 544 61030 N387 L S S Q P I S N T D P V L K S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180249 1045 119369 H395 V V A S K T G H P T A S T T F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.9 20 88.8 N.A. 87.7 20.1 N.A. 71.7 55.7 41.5 N.A. N.A. N.A. N.A. N.A. 23
Protein Similarity: 100 87.4 32.9 92.9 N.A. 93 32.3 N.A. 79.6 65.8 56.8 N.A. N.A. N.A. N.A. N.A. 32.9
P-Site Identity: 100 0 0 6.6 N.A. 93.3 6.6 N.A. 6.6 80 0 N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 20 13.3 13.3 N.A. 100 20 N.A. 6.6 86.6 13.3 N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 10 30 0 20 10 0 0 30 10 10 20 0 0 0 % D
% Glu: 0 10 10 0 10 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % F
% Gly: 10 0 0 0 0 0 20 0 0 0 10 0 0 0 30 % G
% His: 0 0 0 0 0 10 0 10 10 0 0 0 0 0 0 % H
% Ile: 10 20 0 0 0 30 0 10 10 0 0 0 0 0 20 % I
% Lys: 0 0 10 0 10 0 0 10 0 0 0 30 0 20 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 10 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 30 0 10 0 30 0 0 0 0 10 10 0 % N
% Pro: 0 0 0 0 10 20 0 0 20 30 10 10 40 0 10 % P
% Gln: 0 10 10 20 0 0 40 0 10 0 30 0 20 0 20 % Q
% Arg: 10 0 0 0 30 0 30 0 0 10 0 10 0 40 0 % R
% Ser: 0 10 10 10 10 0 10 0 0 0 0 10 0 0 10 % S
% Thr: 30 0 20 20 0 10 0 20 10 50 0 10 10 10 0 % T
% Val: 30 30 0 10 10 10 0 10 10 0 10 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _