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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM14E All Species: 2.12
Human Site: S54 Identified Species: 4.24
UniProt: Q6UXP3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UXP3 NP_001116700.1 125 13608 S54 E L A G L D A S Q P S R N P K
Chimpanzee Pan troglodytes XP_001167565 114 12030 L44 P S L A A G L L F G S L A G L
Rhesus Macaque Macaca mulatta XP_001094148 114 12006 L44 P S L A A G L L F G S L A G L
Dog Lupus familis XP_535885 114 11732 F44 P S L A A G L F F G S L A G L
Cat Felis silvestris
Mouse Mus musculus Q9CQN6 114 11623 F44 P S L A A G L F F G G L A G L
Rat Rattus norvegicus Q924P2 115 11757 F45 S L A A G L F F G G L A G L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514626 142 14235 S51 G Y A A L V A S G G I I G Y A
Chicken Gallus gallus XP_418940 107 11066 F37 S L V A G L L F G S L A G L G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q0P436 107 10663 F37 S L A A G L V F G G L A G F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1K0 112 11563 G42 L A F G A L L G Y G A H L N S
Honey Bee Apis mellifera XP_001120404 113 11638 Y43 I F G S V L G Y G A Y Q T S Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795741 101 10475 A31 A G S T M S L A S G L L F G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28 28.7 39.2 N.A. 36 39.2 N.A. 33 32.7 N.A. 32 N.A. 30.3 32.7 N.A. 29.6
Protein Similarity: 100 48 50.4 55.2 N.A. 52.7 53.5 N.A. 47.1 41.5 N.A. 46.4 N.A. 40 48.7 N.A. 44.8
P-Site Identity: 100 6.6 6.6 6.6 N.A. 0 13.3 N.A. 26.6 6.6 N.A. 13.3 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 6.6 6.6 6.6 N.A. 0 13.3 N.A. 26.6 6.6 N.A. 13.3 N.A. 13.3 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 34 67 42 0 17 9 0 9 9 25 34 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 9 9 0 0 0 9 42 34 0 0 0 9 9 0 % F
% Gly: 9 9 9 17 25 34 9 9 42 75 9 0 34 42 25 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 9 34 34 0 17 42 59 17 0 0 34 42 9 17 34 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % N
% Pro: 34 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 25 34 9 9 0 9 0 17 9 9 34 0 0 9 9 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 0 9 0 9 9 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 9 9 0 9 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _